ReviewExperimental physiology2023
The sympathetic nervous system in healthy and hypertensive pregnancies: physiology or pathology?
Review in Experimental physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Muscle sympathetic nerve activity during pregnancy: A systematic review and meta-analysis.Physiological reports · 2023Pooled it
- Impact of Gestational Weight Gain and Maternal Weight on Sympathetic Adaptations.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Electric Field-Induced Release and Measurement Liquid Biopsy of Urinary Transcriptomics and Key Proteins from Normal and High-risk Pregnant Women.Reproductive sciences (Thousand Oaks, Calif.) · 2026Article
- Vascular health and exercise in females throughout the lifespan: Exploring puberty, pregnancy and menopause.Experimental physiology · 2026Review
- Temporal Dynamics of Catestatin Across Gestation: Links to Metabolic and Hemodynamic Adaptation.Life (Basel, Switzerland) · 2026Article
- The impact of ambient temperature on preeclampsia admissions in cold regions of developing countries: a distributed lag analysis in Harbin, China.BMC pregnancy and childbirth · 2026Article
- Evaluation of age effect on circulating catecholamines' network in pregnant mares.Veterinary research communications · 2025Article
- Analysis of Circulating Catestatin in Early Pregnancy: A Preliminary Investigation.Biomedicines · 2024Article
- Treating Erythromelalgia with Interosseous Membrane Stimulation: An Autonomic Basis for the Condition and Its Treatment.Medical acupuncture · 2024Article
- Multifractal analysis of heart rate variability in pregnancy during sleep.Frontiers in cardiovascular medicine · 2024Article
- Causes and consequences of sympathoexcitation across the lifespan: Physiological or pathological?Experimental physiology · 2023Article
- The sympathetic nervous system in healthy and hypertensive pregnancies: physiology or pathology?Experimental physiology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
NEW
findingsWhat is the topic of this review? Sympathoexcitation in both healthy and hypertensive pregnancies, and concurrent adaptations along the neurovascular cascade. What advances does it highlight? Known and plausible adaptations along the neurovascular cascade which may offset elevated MSNA in normotensive pregnancy while also highlighting knowledge gaps regarding understudied pathways. ABSTRACT: The progression from conception through to the postpartum period represents an extraordinary period of physiological adaptation in the mother to support the growth and development of the fetus. Healthy, normotensive human pregnancies are associated with striking increases in both plasma volume and sympathetic nerve activity, yet normal or reduced blood pressure; it represents a unique period of apparent healthy sympathetic hyperactivity. However, how this normal blood pressure is achieved in the face of sympathoexcitation, and the mechanisms responsible for this increased activity are unclear. Importantly, sympathetic activation has been implicated in hypertensive pregnancy disorders - the leading causes of maternal-fetal morbidity and mortality in the developed world. An understudied link between pregnancy and the development of maternal hypertension may lie in the sympathetic nervous system regulation of blood pressure. This brief review presents the latest data on sympathoexcitation in both healthy and hypertensive pregnancies, and concurrent adaptations along the neurovascular cascade.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.