Evidence map›Paper›PMID 36459299›Full record

ArticleEJNMMI radiopharmacy and chemistry2022

A simple and automated method for

Scott W McNeil, Michiel Van de Voorde, Chengcheng Zhang, Maarten Ooms, François Bénard, Valery Radchenko, Hua Yang

Abstract read
In one paragraph

Article in EJNMMI radiopharmacy and chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Practical Aspects ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Review
  5. Quantitative SPECT imaging ofEJNMMI physics · 2024
    Article
  6. Review
  7. Review
  8. Preclinical Evaluation of [Molecules (Basel, Switzerland) · 2023
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Scott W McNeilLife Sciences Division, TRIUMF, 4004 Wesbrook Mall, Vancouver, BC, V6T 2A3, Canada.
Michiel Van de VoordeNURA Research Group, Belgian Nuclear Research Center (SCK CEN), Boeretang 200, 2400, Mol, Belgium.
Chengcheng ZhangDepartment of Molecular Oncology, British Columbia Cancer Research Institute, 675 West 10th Ave., Vancouver, BC, V5Z 1L3, Canada.
Maarten OomsNURA Research Group, Belgian Nuclear Research Center (SCK CEN), Boeretang 200, 2400, Mol, Belgium.
François BénardDepartment of Molecular Oncology, British Columbia Cancer Research Institute, 675 West 10th Ave., Vancouver, BC, V5Z 1L3, Canada.
Valery RadchenkoLife Sciences Division, TRIUMF, 4004 Wesbrook Mall, Vancouver, BC, V6T 2A3, Canada.
Hua YangLife Sciences Division, TRIUMF, 4004 Wesbrook Mall, Vancouver, BC, V6T 2A3, Canada. hyang@triumf.ca.ORCID http://orcid.org/0000-0003-1833-9515

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN-2018-04997Natural Sciences and Engineering Research Council of Canada RGPIN-2022-03887
6 · The paper itself

Abstract

background

resultsWe first tested the distribution coefficients on TK211 and TK212 resins for the separation of Gd, Tb, and Dy, and subsequently developed a method to separate these metal ions, with an additional TK221 resin to concentrate the final product. A side-by-side comparison of the products purified using this new method with the HPIC method was undertaken, assessing the radionuclidic purity, chemical purity regarding Gd and Dy, and labeling efficiency with a standard chelate (DOTA) and a novel chelate (crown). The two methods have comparable radionuclidic purity and labeling efficiency. The small SPE column method reduced Gd content to nanogram level, although still higher than the HPIC method. An ICP-MS method to quantify

conclusions

Indexed as

161TbAutomationICP-MSRadionuclide purification

Identifiers

PMID36459299
PMCPMC9718904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.