Evidence map›Paper›PMID 36459245›Full record

ArticlePediatric nephrology (Berlin, Germany)2023

Family functioning and quality of life among children with nephrotic syndrome during the first pandemic wave.

Nowrin F Aman, Jessica Fitzpatrick, Isabel de Verteuil, Jovanka Vasilevska-Ristovska, Tonny Hue Minh Banh, Daphne J Korczak, Rulan S Parekh

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. The impact of the SARS-CoV2 pandemic on the mental health of scoliosis patients in Germany.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Nowrin F AmanChild Health and Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.
Jessica FitzpatrickChild Health and Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.
Isabel de VerteuilChild Health and Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.
Jovanka Vasilevska-RistovskaChild Health and Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.
Tonny Hue Minh BanhChild Health and Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.
Daphne J KorczakDepartment of Psychiatry, Hospital for Sick Children, Toronto, ON, Canada.
Rulan S ParekhChild Health and Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada. rulan.parekh@wchospital.ca.ORCID http://orcid.org/0000-0001-6313-5752
Hospital for Sick Children · CAUniversity of California, San Francisco · USUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuring the SARS-CoV-2 global pandemic, one of the longest lockdowns worldwide occurred in Ontario, Canada, during the first wave. For parents and children managing care at home and at risk for COVID-19, the impact on their psychosocial functioning is unknown.

methodsA total of 122 families of children aged 2-18 years were enrolled as part of the prospective cohort of childhood nephrotic syndrome and completed a survey during the first wave of the pandemic (August 21-December 10), 2020. In a subset, 107 families had data available pre-pandemic to assess change. Validated measures included the McMaster Family Assessment Device (FAD) for parents and children ≥ 12 years for family functioning, the Patient Health Questionnaire for Depression and Anxiety (PHQ-4) for both parent and child, and Pediatric Quality of Life Inventory (PEDSQL™-V4) for children only. Scores were compared using Student's t-test or the Mann-Whitney U test, as appropriate.

resultsAmong the 107 children, 71% were male with a mean age of 9 years old at the time of questionnaire completion, and the mean age of parents was 41 years old. Parents and children reported that family functioning improved during COVID (parent: p < 0.01; child: p = 0.05). Children's overall HRQOL declined (p = 0.04), specifically increased sleep disruption (p = 0.01). Increasing child age was associated with a greater sleep disruption (β =  - 1.6 [IQR: - 2.6, - 0.67]) and a related decrease in QOL (β =  - 1.0 [IQR: - 1.7, - 0.2]), adjusted for sex.

conclusionsDespite the positive effects of family dynamics during the first wave, there were negative effects of sleep disruptions and reduced quality of life in children, especially among older children. A higher resolution version of the Graphical abstract is available as Supplementary information.

Indexed as

COVID-19Nephrotic SyndromeAdolescentAdultChildCommunicable Disease ControlFemaleHumansMalePandemicsParentsProspective StudiesQuality of LifeSARS-CoV-2Surveys and QuestionnairesChronic diseaseCOVID-19Family functioningNephrotic syndromeQuality of lifeWell-being

Identifiers

PMID36459245
PMCPMC9716160
OpenAlexW4310589050

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.