ReviewPediatric nephrology (Berlin, Germany)2023
Glomerular hyperfiltration: part 1 - defining the threshold - is the sky the limit?
Review in Pediatric nephrology (Berlin, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 29 citations in OpenAlex.
- Predictors of augmented renal clearance based on iohexol plasma clearance in critically ill children.Pediatric nephrology (Berlin, Germany) · 2024Trial
- Cystatin C and glomerular hyperfiltration in preterm-born adults.Pediatric nephrology (Berlin, Germany) · 2026Article
- Examining commonly used equations for estimating the glomerular filtration rate (GFR) in a healthy cohort of children and adolescents.BMC nephrology · 2026Observational
- Early signs of nephropathy in adolescents with obesity.International journal of obesity (2005) · 2026Article
- The Longitudinal Effect of APOL1 Risk Alleles on Sickle Cell Anemia-Associated Kidney Function.American journal of hematology · 2026Observational
- Performance of creatinine and cystatin C-based equations for estimating high levels of glomerular filtration rate in Congolese adults with sickle cell disease.Clinical kidney journal · 2026Article
- Renal complications in pediatric sickle cell disease: results from a single-center study.Annals of hematology · 2026Article
- Which glomerular filtration rate estimation equations should be used in youth with type 1 diabetes?Pediatric nephrology (Berlin, Germany) · 2026Article
- Performance of creatinine and cystatin C-based equations to estimate glomerular filtration rate in African children with sickle cell anemia.Pediatric nephrology (Berlin, Germany) · 2026Article
- Longitudinal evaluation of glomerular filtration rate across adolescence and early adulthood in youth with type 1 diabetes: associations with clinical and social risk factors.Frontiers in endocrinology · 2026Article
- Long-term kidney side effects of allogeneic hematopoietic stem cell transplantation in children.Pediatric nephrology (Berlin, Germany) · 2025Article
- Measuring and estimating the GFR in children: state of the art in 2025.Pediatric nephrology (Berlin, Germany) · 2025Review
- The effects of valproic acid and levetiracetam treatments on kidney functions in children with epilepsy.Pakistan journal of medical sciences · 2025Article
- Switching to the CKD-EPI but Not Modified FAS eGFR Formula Underdetects CKD Among Adolescents and Young Adults in México.Children (Basel, Switzerland) · 2025Article
- Fibronectin Glomerulopathy Without Typical Renal Biopsy Features in a 4-Year-Old Girl with Incidentally Discovered Proteinuria and a G417VInternational journal of molecular sciences · 2025Article
- Calculation of Integral Indicators of the Metabolic Status and Filtration Function of Kidneys in Patients with a Combat Mine-Explosive Injury who Lost Significant Body Weight due to Limb Amputation.Acta medica Lituanic · 2025Article
- Estimating glomerular filtration in young people.Clinical kidney journal · 2024Article
- Renal impairment is prevalent in pediatric NAFLD/MASLD and associated with disease severity.Journal of pediatric gastroenterology and nutrition · 2024Article
- Cardiometabolic comorbidities and complications of obesity and chronic kidney disease (CKD).Journal of clinical & translational endocrinology · 2024Review
- Kidney Measurement and Glomerular Filtration Rate Evolution in Children with Polycystic Kidney Disease.Children (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glomerular hyperfiltration (GHF) is an increase in single-nephron glomerular filtration rate (GFR) that occurs in both physiological states and pathological states. Whole-kidney GHF is often used as a surrogate for single-nephron hyperfiltration since determining single-nephron GFR is impossible in routine clinical care. A clear definition (read threshold) of GHF is lacking. The aim of the first part of this review was to find evidence for defining the threshold for GHF, based on literature review, including systematic reviews and meta-analysis data, with both measured and estimated GFR. The consensus pediatric threshold for GHF as obtained from reviews, measured and estimated GFR studies, can reliably be set to 135 mL/min/1.73 m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.