Evidence map›Paper›PMID 36458689›Full record

ArticleeLife2022

Evgeniya N Andreyeva, Alexander V Emelyanov, Markus Nevil, Lu Sun, Elena Vershilova, Christina A Hill, Michael-C Keogh, Robert J Duronio, Arthur I Skoultchi, Dmitry V Fyodorov

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. eLife · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Evgeniya N Andreyeva *Department of Cell Biology, Albert Einstein College of Medicine, Bronx, United States.
Alexander V Emelyanov *Department of Cell Biology, Albert Einstein College of Medicine, Bronx, United States.
Markus NevilUNC-SPIRE, University of North Carolina, Chapel Hill, United States.
Lu SunEpiCypher, Durham, United States.
Elena VershilovaDepartment of Cell Biology, Albert Einstein College of Medicine, Bronx, United States.
Christina A HillIntegrative Program for Biological and Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, United States.
Michael-C KeoghEpiCypher, Durham, United States.ORCID 0000-0002-2219-8623
Robert J DuronioIntegrative Program for Biological and Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, United States.
Arthur I SkoultchiDepartment of Cell Biology, Albert Einstein College of Medicine, Bronx, United States.
Dmitry V FyodorovDepartment of Cell Biology, Albert Einstein College of Medicine, Bronx, United States.ORCID 0000-0002-3080-1787
Albert Einstein College of Medicine · USEpiCypher (United States) · USUniversity of North Carolina at Chapel Hill · US

Funding

SEEDING POSTDOCTORAL INNOVATORS IN RESEARCH &EDUCATIONK12GM000678 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DONALD T LYSLE, Kathryn Joanna Reissner · 1999 to 2026
$30.9M
Chromatin Transitions during Early Embryonic Development in Drosophila melanogasterR01GM074233 · NIGMS · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI FYODOROV, DMITRY V · 2005 to 2021
$5.8M
Epigenetic Control of the Cell Cycle During Animal DevelopmentR35GM145258 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Robert J Duronio · 2022 to 2026
$2.3M
Functions of Mammalian H1 Linker Histones in Gene Regulation and Chromatin ActivityR01GM147165 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI SKOULTCHI, ARTHUR I · 2022 to 2025
$2.1M
Cancer Epigenetics Training GrantT32CA217824 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WEISSMAN, BERNARD E. · 2017 to 2021
$1.8M
A nucleosome sliding assay platform to screen inhibitors of SWI/SNF chromatin remodeling complexesR44GM123869 · NIGMS · EPICYPHER, INC. · PI KEOGH, MICHAEL-CHRISTOPHER · 2018 to 2019
$1.7M
Regulation of Nuclear Functions by Drosophila Linker Histone H1R01GM129244 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI FYODOROV, DMITRY V, SKOULTCHI, ARTHUR I · 2018 to 2021
$1.5M
Regulation of Metazoan DNA Replication by ChromatinR01GM124201 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DURONIO, ROBERT J · 2018 to 2021
$1.2M
NCI NIH HHS T32 CA217824NIGMS NIH HHS K12 GM000678NIGMS NIH HHS R01 GM074233NIGMS NIH HHS R01 GM124201NIGMS NIH HHS R01 GM129244NIGMS NIH HHS R01 GM147165NIGMS NIH HHS R35 GM145258NIGMS NIH HHS R44 GM123869NIH HHS K12 GM000678NIH HHS R01 GM124201NIH HHS R44 GM123869NIH HHS T32 CA217824
6 · The paper itself

Abstract

Asynchronous replication of chromosome domains during S phase is essential for eukaryotic genome function, but the mechanisms establishing which domains replicate early versus late in different cell types remain incompletely understood. Intercalary heterochromatin domains replicate very late in both diploid chromosomes of dividing cells and in endoreplicating polytene chromosomes where they are also underreplicated.

Indexed as

DrosophilaDrosophila ProteinsAnimalsChromatinDNA-Binding ProteinsDNA ReplicationDrosophila melanogasterEuchromatinHeterochromatinChromatinDNA-Binding ProteinsDrosophila ProteinsEuchromatinHeterochromatinSuUR protein, DrosophilachromosomesD. melanogasterDNA replicationgene expressiongeneticsgenomicsinsulatorMod(Mdg4)polytene chromosomesSUURunder-replication

Identifiers

PMID36458689
PMCPMC9917439
OpenAlexW4310597693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.