Evidence map›Paper›PMID 36458573›Full record

ArticleIslets2022

Genome-edited zebrafish model of

Jennifer M Ikle, Robert C Tryon, Soma S Singareddy, Nathaniel W York, Maria S Remedi, Colin G Nichols

Open access · goldAbstract read
In one paragraph

Article in Islets, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jennifer M IkleDepartment of Cell Biology and Physiology, Washington University in St. Louis, St. Louis, Missouri, USA.
Robert C TryonDepartment of Cell Biology and Physiology, Washington University in St. Louis, St. Louis, Missouri, USA.
Soma S SingareddyDepartment of Cell Biology and Physiology, Washington University in St. Louis, St. Louis, Missouri, USA.
Nathaniel W YorkDepartment of Cell Biology and Physiology, Washington University in St. Louis, St. Louis, Missouri, USA.
Maria S RemediDepartment of Cell Biology and Physiology, Washington University in St. Louis, St. Louis, Missouri, USA.
Colin G NicholsDepartment of Cell Biology and Physiology, Washington University in St. Louis, St. Louis, Missouri, USA.
Washington University in St. Louis · US

Funding

Training of the Pediatric Physician-ScientistT32HD043010 · NICHD · WASHINGTON UNIVERSITY · PI MARK E. LOWE · 2002 to 2026
$6.4M
Role of vascular KATP channels in Alzheimer’s neurodegeneration and dementiaR35HL140024 · NHLBI · WASHINGTON UNIVERSITY · PI NICHOLS, COLIN G · 2018 to 2023
$5.9M
Beta-Cell Exhaustion and Glucotoxicity in DiabetesR01DK123163 · NIDDK · WASHINGTON UNIVERSITY · PI Maria Sara Remedi · 2020 to 2026
$2.8M
BETA-CELL EXHAUSTION AND GLUCOTOXICITY IN DIABETESR01DK098584 · NIDDK · WASHINGTON UNIVERSITY · PI REMEDI, MARIA SARA · 2013 to 2017
$1.7M
ELECTRICAL CONTROL OF INSULIN SECRETIONR01DK109407 · NIDDK · WASHINGTON UNIVERSITY · PI NICHOLS, COLIN G · 2016 to 2019
$1.4M
NHLBI NIH HHS R35 HL140024NICHD NIH HHS T32 HD043010NIDDK NIH HHS R01 DK098584NIDDK NIH HHS R01 DK109407NIDDK NIH HHS R01 DK123163
6 · The paper itself

Abstract

ATP-sensitive potassium channel (K

Indexed as

Glucose IntoleranceHyperinsulinismAdenosine TriphosphateAnimalsDisease Models, AnimalMiceMice, KnockoutMice, TransgenicSulfonylurea ReceptorsZebrafishAbcc8 protein, mouseAdenosine TriphosphateSulfonylurea Receptorscalcium channelsinsulin secretionKATPmetabolismpancreaszebrafish

Identifiers

PMID36458573
PMCPMC9721409
OpenAlexW4310546462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.