Evidence map›Paper›PMID 36458570›Full record

ArticleEmerging microbes & infections2023

Place of magistral preparations to continue the treatment if the drug is commercially stopped worldwide? A case report of a 10-year-old child with subacute sclerosing panencephalitis (SSPE) requiring inosiplex.

Renan Le Cras, Roseline Mazet, Fanny Dubois-Teklali, Cécile Sabourdy, Sébastien Chanoine, Audrey Lehmann, Agathe Morin, Julien Leenhardt, Marjorie Durand, Marie-Dominique Desruet and 1 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Emerging microbes & infections, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 77% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Renan Le CrasPharmacy Department, Grenoble University Hospital, Grenoble, France.
Roseline MazetPharmacy Department, Grenoble University Hospital, Grenoble, France.ORCID 0000-0002-1841-6691
Fanny Dubois-TeklaliPediatric Neurology Unit, Grenoble University Hospital, Grenoble, France.ORCID 0000-0002-4057-2375
Cécile SabourdyNeurology Unit, Grenoble University Hospital, Grenoble, France.ORCID 0000-0002-6781-9761
Sébastien ChanoinePharmacy Department, Grenoble University Hospital, Grenoble, France.ORCID 0000-0001-7708-9777
Audrey LehmannPharmacy Department, Grenoble University Hospital, Grenoble, France.ORCID 0000-0003-4237-4329
Agathe MorinPharmacy Department, Grenoble University Hospital, Grenoble, France.
Julien LeenhardtPharmacy Department, Grenoble University Hospital, Grenoble, France.
Marjorie DurandPharmacy Department, Grenoble University Hospital, Grenoble, France.
Marie-Dominique DesruetPharmacy Department, Grenoble University Hospital, Grenoble, France.
Pierrick BedouchPharmacy Department, Grenoble University Hospital, Grenoble, France.ORCID 0000-0003-2245-0160
Centre Hospitalier Universitaire de Grenoble · FRCentre National de la Recherche Scientifique · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Subacute sclerosing panencephalitis (SSPE) is a late-onset and fatal viral disease caused by persistent infection of the central nervous system by measles virus (MeV). We present the case of a 10-year-old child from South Asia affected by SSPE, stabilized with a combination of intrathecal interferon-α2b (INF-α2b) injections and oral inosiplex and how we continued the treatment when inosiplex was commercially stopped worldwide.

Indexed as

Inosine PranobexSubacute Sclerosing PanencephalitisAsia, SouthernChildHumansInterferon-alphaInosine PranobexInterferon-alphainosine pranobexInosiplexmagistral preparationspeciality commercially stoppedsubacute sclerosing panencephalitis (SSPE)

Identifiers

PMID36458570
PMCPMC9788679
OpenAlexW4310599131

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.