Evidence map›Paper›PMID 36458550›Full record

ReviewHypertension (Dallas, Tex. : 1979)2023

The Microsoft Research Aurora Project: Important Findings on Cuffless Blood Pressure Measurement.

Ramakrishna Mukkamala, Sanjeev G Shroff, Cederick Landry, Konstantinos G Kyriakoulis, Alberto P Avolio, George S Stergiou

Abstract readReview
In one paragraph

Review in Hypertension (Dallas, Tex. : 1979), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Remote Blood Pressure Monitoring: A Comprehensive Review.American journal of hypertension · 2026
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Digital hypertension - what we need for the high-quality management of hypertension in the new era.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ramakrishna MukkamalaDepartment of Bioengineering, University of Pittsburgh, PA (R.M., S.G.S., C.L.).
Sanjeev G ShroffDepartment of Bioengineering, University of Pittsburgh, PA (R.M., S.G.S., C.L.).ORCID 0000-0003-1868-3826
Cederick LandryDepartment of Bioengineering, University of Pittsburgh, PA (R.M., S.G.S., C.L.).
Konstantinos G KyriakoulisHypertension Center STRIDE-7, School of Medicine, Third Department of Medicine, Sotiria Hospital, National and Kapodistrian University of Athens, Athens, Greece (K.G.K., G.S.S.).ORCID 0000-0001-8986-2704
Alberto P AvolioMacquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, NSW, Australia (A.P.A.).ORCID 0000-0002-8311-2010
George S StergiouHypertension Center STRIDE-7, School of Medicine, Third Department of Medicine, Sotiria Hospital, National and Kapodistrian University of Athens, Athens, Greece (K.G.K., G.S.S.).ORCID 0000-0002-6132-0038

Funding

A Smartphone-Based Device for Cuff-Less and Calibration-Free Blood Pressure MonitoringR01HL146470 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MUKKAMALA, RAMAKRISHNA · 2019 to 2022
$1.1M
NHLBI NIH HHS R01 HL146470
6 · The paper itself

Abstract

Conventional blood pressure (BP) measurement devices based on an inflatable cuff only provide a narrow view of the continuous BP profile. Cuffless BP measuring technologies could permit numerous BP readings throughout daily life and thereby considerably improve the assessment and management of hypertension. Several wearable cuffless BP devices based on pulse wave analysis (applied to a photoplethysmography or tonometry waveform) with or without use of pulse arrival time are now available on the market. The key question is: Can these devices provide accurate measurement of BP? Microsoft Research recently published a complex article describing perhaps the most important and highest resource project to date (Aurora Project) on assessing the accuracy of several pulse wave analysis and pulse wave analysis-pulse arrival time devices. The overall results from 1125 participants were clear-cut negative. The present article motivates and describes emerging cuffless BP devices and then summarizes the Aurora Project. The study methodology and findings are next discussed in the context of regulatory-cleared devices, physiology, and related studies, and the study strengths and limitations are pinpointed thereafter. Finally, the implications of the Aurora Project are briefly stated and recommendations for future work are offered to finally realize the considerable potential of cuffless BP measurement in health care.

Indexed as

Blood Pressure DeterminationHypertensionBlood PressureHeart RateHumansPulse Wave AnalysisSphygmomanometersblood pressure determinationcalibrationcufflesspulse arrival timepulse wave analysisvalidation studywearable electronic devices

Identifiers

PMID36458550
PMCPMC9931644

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.