Evidence map›Paper›PMID 36458282›Full record

ReviewDose-response : a publication of International Hormesis Society

Biophysical Modeling of the Ionizing Radiation Influence on Cells Using the Stochastic (Monte Carlo) and Deterministic (Analytical) Approaches.

Krzysztof W Fornalski, Łukasz Adamowski, Ernest Bugała, Rafał Jarmakiewicz, Marek Kirejczyk, Jakub Kopyciński, Julianna Krasowska, Piotr Kukulski, Łukasz Piotrowski, Julia Ponikowska and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Dose-response : a publication of International Hormesis Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Krzysztof W FornalskiFaculty of Physics, Warsaw University of Technology (WF PW), Poland.ORCID https://orcid.org/0000-0001-7452-0189
Łukasz AdamowskiNational Centre for Nuclear Research (NCBJ), Poland.ORCID https://orcid.org/0000-0002-2195-0959
Ernest BugałaFaculty of Physics, Warsaw University of Technology (WF PW), Poland.
Rafał JarmakiewiczFaculty of Physics, Warsaw University of Technology (WF PW), Poland.
Marek KirejczykNational Centre for Nuclear Research (NCBJ), Poland.
Jakub KopycińskiCenter for Theoretical Physics, Polish Academy of Sciences (CFT PAN), Poland.
Julianna KrasowskaFaculty of Physics, Warsaw University of Technology (WF PW), Poland.
Piotr KukulskiDepartment of Mechanical, Aerospace and Civil Engineering, University of Manchester (MACE UoM), United Kingdom.
Łukasz PiotrowskiFaculty of Physics, Warsaw University of Technology (WF PW), Poland.
Julia PonikowskaFaculty of Physics, Warsaw University of Technology (WF PW), Poland.
Joanna ReszczyńskaMossakowski Medical Research Institute, Polish Academy of Sciences (IMDiK PAN), Poland.
Iwona SłoneckaFaculty of Physics, Warsaw University of Technology (WF PW), Poland.
Paweł WysockiFaculty of Physics, Warsaw University of Technology (WF PW), Poland.
Ludwik DobrzyńskiNational Centre for Nuclear Research (NCBJ), Poland.
Warsaw University of Technology · PLNational Centre for Nuclear Research · PLCenter for Theoretical Physics · PLMossakowski Medical Research Institute, Polish Academy of Sciences · PLUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review article describes our simplified biophysical model for the response of a group of cells to ionizing radiation. The model, which is a product of 10 years of studies, acts as (a) a comprehensive stochastic approach based on the Monte Carlo simulation with a probability tree and (b) the thereof derived detailed deterministic models describing the selected biophysical and radiobiological phenomena in an analytical manner. Specifically, the presented model describes effects such as the risk of neoplastic transformation of cells relative to the absorbed radiation dose, the dynamics of tumor development, the priming dose effect (also called the Raper-Yonezawa effect) based on the introduced adaptive response approach, and the bystander effect. The model is also modifiable depending on users' potential needs.

Indexed as

adaptive responsedose responselow doselow-dose modelingMonte Carloradiation risk

Identifiers

PMID36458282
PMCPMC9706082
OpenAlexW4309731082

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.