Evidence map›Paper›PMID 36458201›Full record

ArticleMolecular therapy oncolytics2022

Dual EGFR- and TfR-targeted gene transfer for sodium iodide symporter gene therapy of glioblastoma.

Rebekka Spellerberg, Teoman Benli-Hoppe, Carolin Kitzberger, Mara Hageneier, Nathalie Schwenk, Özgür Öztürk, Katja Steiger, Gabriele Multhoff, Matthias Eiber, Franz Schilling and 6 more

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy oncolytics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Combined Vorinostat and Chloroquine Inhibit Sodium-Iodide Symporter Endocytosis and Enhance Radionuclide Uptake In Vivo.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Rebekka SpellerbergDepartment of Internal Medicine IV, LMU University Hospital, LMU Munich, Munich, Germany.
Teoman Benli-HoppePharmaceutical Biotechnology, Department of Pharmacy, Centre for System-Based Drug Research, and Centre for Nanoscience, LMU Munich, Munich, Germany.
Carolin KitzbergerDepartment of Internal Medicine IV, LMU University Hospital, LMU Munich, Munich, Germany.
Mara HageneierDepartment of Internal Medicine IV, LMU University Hospital, LMU Munich, Munich, Germany.
Nathalie SchwenkDepartment of Internal Medicine IV, LMU University Hospital, LMU Munich, Munich, Germany.
Özgür ÖztürkPharmaceutical Biotechnology, Department of Pharmacy, Centre for System-Based Drug Research, and Centre for Nanoscience, LMU Munich, Munich, Germany.
Katja SteigerInstitute of Pathology, School of Medicine, Technical University of Munich, Munich, Germany.
Gabriele MulthoffCenter for Translational Cancer Research, Radiation Immuno-Oncology Group, School of Medicine, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Matthias EiberDepartment of Nuclear Medicine, School of Medicine, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Franz SchillingDepartment of Nuclear Medicine, School of Medicine, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Wolfgang A WeberDepartment of Nuclear Medicine, School of Medicine, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Roland E KälinNeurosurgical Research, Department of Neurosurgery, LMU University Hospital, LMU Munich, Munich, Germany.
Rainer GlassNeurosurgical Research, Department of Neurosurgery, LMU University Hospital, LMU Munich, Munich, Germany.
Peter J NelsonDepartment of Internal Medicine IV, LMU University Hospital, LMU Munich, Munich, Germany.
Ernst WagnerPharmaceutical Biotechnology, Department of Pharmacy, Centre for System-Based Drug Research, and Centre for Nanoscience, LMU Munich, Munich, Germany.
Christine SpitzwegDepartment of Internal Medicine IV, LMU University Hospital, LMU Munich, Munich, Germany.
LMU Klinikum · DETUM Klinikum · DECenter for NanoScience · DEGerman Cancer Research Center · DETechnical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sodium iodide symporter (

Indexed as

blood-brain barrierEGFRgene therapygene transferglioblastomananocarrierNISpDNA deliverypolyplexeradioiodinesodium iodide symportertransferrin receptortumor-specific targeting

Identifiers

PMID36458201
PMCPMC9709165
OpenAlexW4308497008

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.