ArticleFrontiers in microbiology2022
Metagenomic next-generation sequencing for identification of central nervous system pathogens in HIV-infected patients.
Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 31 citations in OpenAlex.
- Harnessing next-generation microbial diagnostics to optimize infection management in immunocompromised hosts.Current opinion in infectious diseases · 2026Review
- Diagnostic value of mNGS for CNSIs in hematopoietic stem cell transplant patients.Blood science (Baltimore, Md.) · 2026Article
- A case report: Guillain-Barré syndrome probably associated with TNF inhibitor in Blau syndrome.BMC pediatrics · 2026Article
- Viral encephalitis related to adalimumab in a 16-year-old Crohn's disease patient: case report and literature review.Frontiers in immunology · 2026Review
- Transverse Comparison of Clinical Characteristics and Prognostic Factors in HIV-Infected Patients with Cytomegalovirus Encephalitis in Guangdong, China.Current HIV research · 2026Article
- Metagenomic Next-generation Sequencing in Patients With Infectious Meningoencephalitis: A Comprehensive Systematic Literature Review and Meta-analysis.Open forum infectious diseases · 2025Article
- The role of mycobacteremia screening in enhancing non-tuberculous mycobacteria detection in hospitalized persons with HIV.Frontiers in microbiology · 2025Article
- Application of Metagenomic Next-Generation Sequencing in HIV-Infected Patients with Bloodstream Infections.Infection and drug resistance · 2025Article
- Massive Intracranial Lesion in an AIDS Patient: Diagnostic Challenge Between Brain Tumor and Toxoplasmic Encephalitis Resolved by Empirical Therapy.International medical case reports journal · 2025Article
- BALF metagenomic next-generation sequencing for the diagnosis of pulmonary mycobacterial infection in persons with HIV: a retrospective, diagnostic accuracy study.Frontiers in microbiology · 2025Article
- Proteomic profiling of cerebrospinal fluid uncovers distinctive pathophysiological changes and potential biomarkers in pediatric tubercular meningitis.Frontiers in cellular and infection microbiology · 2025Article
- Research advances and public health strategies in China on WHO priority fungal pathogens.Mycology · 2025Review
- Clinical data and MRI features-based nomogram for differentiation of central nervous system infection and central nervous system involvement in hematological malignancy.Annals of hematology · 2024Article
- Nanopore targeted sequencing-based diagnosis of central nervous system infections in HIV-infected patients.Annals of clinical microbiology and antimicrobials · 2024Article
- Tuberculous meningitis diagnosis and treatment: classic approaches and high-throughput pathways.Frontiers in immunology · 2024Review
- Epstein-Barr virus: To be a trigger of autoimmune glial fibrillary acidic protein astrocytopathy?CNS neuroscience & therapeutics · 2023Article
- Metagenomic next-generation sequencing and proteomics analysis in pediatric viral encephalitis and meningitis.Frontiers in cellular and infection microbiology · 2023Article
- Case Report: A case ofFrontiers in cellular and infection microbiology · 2023Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although considerable interest in metagenomic next-generation sequencing (mNGS) has been attracted in recent years, limited data are available regarding the performance of mNGS in HIV-associated central nervous system (CNS) infection. Here, we conducted a retrospectively analyzing of the cerebrospinal fluid (CSF) mNGS reports and other clinical data from 80 HIV-infected patients admitted to the Second Hospital of Nanjing, China from March, 2018 to March, 2022. In our study, CSF mNGS reported negative result, mono-infection, and mixed infection in 8.8, 36.2, and 55% of the patients, respectively.
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