Evidence map›Paper›PMID 36457982›Full record

ArticleArchives of medical science : AMS2022

MiR-146a and miR-155 polymorphisms in Egyptian patients with Behcet's disease.

Olfat G Shaker, Omayma O Abdelaleem, Nermeen A Fouad, Naglaa A Ahmed, Hoda A Hussein, Enas G Ibrahem, Abdelrahmaan A Mohamed, Othman M Ahmed, Doaa Y Ali

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of medical science : AMS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Olfat G ShakerDepartment of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Omayma O AbdelaleemDepartment of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Fayoum University, Faiyum, Egypt.
Nermeen A FouadDepartment of Rheumatology and Rehabilitation, Faculty of Medicine, Fayoum University, Faiyum, Egypt.
Naglaa A AhmedDepartment of Medical Physiology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Hoda A HusseinDepartment of Internal Medicine, Faculty of Medicine, Fayoum University, Faiyum, Egypt.
Enas G IbrahemDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Fayoum University, Faiyum, Egypt.
Abdelrahmaan A MohamedDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Fayoum University, Faiyum, Egypt.
Othman M AhmedDepartment of Clinical Pathology, Faculty of Medicine, Fayoum University, Faiyum, Egypt.
Doaa Y AliDepartment of Clinical Pathology, Faculty of Medicine, Fayoum University, Faiyum, Egypt.
Cairo University · EGFayoum University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The current study was designed to analyze whether polymorphisms of miR-146a and miR-155 are related to Behçet's disease (BD) in the Egyptian population. Material and methods: A total of 96 unrelated BD patients and 100 healthy subjects were genotyped for miR-146a (rs2910164) and miR-155 (rs767649) using real-time polymerase chain reaction. Results: The results showed significant elevation in the frequency of rs2910164 GG and CC genotypes in BD patients compared with controls (adjusted OR = 22.156, 95% CI: 4.728-103.818; Conclusions: miR-146a (rs2910164) and miR-155 (rs767649) are likely to play an important role in the Egyptian population in development of BD and also influence disease severity.

Indexed as

Behçet’s diseasemiR-146amiR-155polymorphism

Identifiers

PMID36457982
PMCPMC9710268
OpenAlexW3137873216

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.