Evidence map›Paper›PMID 36457866›Full record

ArticleFrontiers in neurology2022

Elevated plasma D-dimer levels in patients with anti-N-methyl-D-aspartate receptor encephalitis.

Yingzhe Shao, Juan Du, Yajun Song, Yanfei Li, Lijun Jing, Zhe Gong, Ranran Duan, Yaobing Yao, Yanjie Jia, Shujie Jiao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Amyloid and Tau as cerebrospinal fluid biomarkers in anti-N-Methyl-D-aspartate receptor encephalitis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yingzhe ShaoDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Juan DuDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yajun SongDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yanfei LiDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Lijun JingDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhe GongDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Ranran DuanDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yaobing YaoDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yanjie JiaDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Shujie JiaoDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
First Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: We aimed to explore the difference in coagulation function between healthy individuals and patients with anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis and its relationship with disease severity. Methods: We retrospectively compared coagulation function in 161 patients with first-attack anti-NMDAR encephalitis and 178 healthy individuals. The association between D-dimer levels and disease severity was analyzed using binary logistic regression. Receiver operating characteristic (ROC) curves were used to analyze the predictive value of D-dimer levels for the severity of anti-NMDAR encephalitis. Results: Compared to control individuals, patients with anti-NMDAR encephalitis had higher D-dimer levels (median 0.14 vs. 0.05 mg/L, Conclusion: Serum D-dimer and neutrophil levels were independent predictors of disease severity in patients with first-attack anti-NMDAR encephalitis.

Indexed as

anti-N-methyl-D-aspartate receptor encephalitiscalciumD-dimereosinophilsinflammationneutrophil

Identifiers

PMID36457866
PMCPMC9707621
OpenAlexW4309109911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.