Evidence map›Paper›PMID 36457702›Full record

ReviewMolecular therapy. Nucleic acids2022

Decoding microRNAs in autism spectrum disorder.

Jinyu Li, Xiaohui Xu, Jiane Liu, Sudan Zhang, Xiaohua Tan, Zhiqiang Li, Jian Zhang, Zheng Wang

Open access · goldAbstract readReview
In one paragraph

Review in Molecular therapy. Nucleic acids, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
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  5. Review
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  9. Article
  10. Article
  11. Review
  12. GnRH and Cognition.Endocrinology · 2025
    Review
  13. Article
  14. Article
  15. Review
  16. Small Differences and Big Changes: The Many Variables of MicroRNA Expression and Function in the Brain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jinyu LiDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, Shandong 266071, China.
Xiaohui XuDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, Shandong 266071, China.
Jiane LiuDepartment of Reproductive Medicine, the Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China.
Sudan ZhangDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, Shandong 266071, China.
Xiaohua TanDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, Shandong 266071, China.
Zhiqiang LiThe Affiliated Hospital of Qingdao University & the Biomedical Sciences Institute of Qingdao University, Qingdao Branch of SJTU Bio-X Institutes, Qingdao University, Qingdao, Shandong 266003, China.
Jian ZhangDepartment of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong 510515, China.
Zheng WangDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, Shandong 266071, China.
Qingdao University · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorder (ASD)-a congenital mental disorder accompanied by social dysfunction and stereotyped behaviors-has attracted a great deal of attention worldwide. A combination of genetic and environmental factors may determine the pathogenesis of ASD. Recent research of multiple ASD models indicates that microRNAs (miRNAs) play a central role at the onset and progression of ASD by repressing the translation of key mRNAs in neural development and functions. As such, miRNAs show great potential to serve as biomarkers for ASD diagnosis or prognosis and therapeutic targets for the treatment of ASD. In this review, we discuss the regulatory mechanisms by which miRNAs influence ASD phenotypes through various

Indexed as

ASDbiomarkerdisease modelingmiRNAMT: Non-coding RNAstherapeutic strategies

Identifiers

PMID36457702
PMCPMC9685394
OpenAlexW4308458520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.