Evidence map›Paper›PMID 36457594›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

Vasorelaxant and Antihypertensive Effects of Bergenin on Isolated Rat Aorta and High Salt-Induced Hypertensive Rats.

Taseer Ahmad, Rahila Qayyum, Taous Khan, Mater H Mahnashi, Mohammed M Jalal, Malik A Altayar, Osama M Alshehri, Abdul Jabbar Shah

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Taseer AhmadDepartment of Pharmacy, COMSATS University Islamabad, Abbottabad Campus, University Road, Abbottabad, KPK 22060, Pakistan.
Rahila QayyumDepartment of Pharmacy, COMSATS University Islamabad, Abbottabad Campus, University Road, Abbottabad, KPK 22060, Pakistan.
Taous KhanDepartment of Pharmacy, COMSATS University Islamabad, Abbottabad Campus, University Road, Abbottabad, KPK 22060, Pakistan.ORCID https://orcid.org/0000-0002-2007-4838
Mater H MahnashiDepartment of Pharmaceutical Chemistry, School of Pharmacy, Najran University, Najran, Saudi Arabia.ORCID https://orcid.org/0000-0002-3095-5604
Mohammed M JalalDepartment of Medical Laboratory Technology, Faculty of Applied Medical Sciences, University of Tabuk, Tabuk, Saudi Arabia.
Malik A AltayarDepartment of Medical Laboratory Technology, Faculty of Applied Medical Sciences, University of Tabuk, Tabuk, Saudi Arabia.ORCID https://orcid.org/0000-0002-3394-0686
Osama M AlshehriDepartment of Clinical Laboratory Sciences, Collage of Applied Medical Science, Najran University, Najran, Saudi Arabia.
Abdul Jabbar ShahDepartment of Pharmacy, COMSATS University Islamabad, Abbottabad Campus, University Road, Abbottabad, KPK 22060, Pakistan.ORCID https://orcid.org/0000-0002-6032-3915
COMSATS University Islamabad · PKNajran University · SAUniversity of Tabuk · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bergenin is a phenolic glycoside that has been reported to be present in some medicinal plants which are traditionally used for their antihypertensive actions. So, bergenin was investigated for antihypertensive and vasorelaxant experiments in a rat model. Bergenin produced a significant fall in the mean arterial pressure (MAP) of rats. To explore the involvement of NO and muscarinic receptors, rats were pretreated with L-NAME and atropine

Identifiers

PMID36457594
PMCPMC9708344
OpenAlexW4309650728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.