Evidence map›Paper›PMID 36457448›Full record

ArticleJournal of obstetrics and gynaecology of India2022

Superficial Spreading, Microinvasive CIN 3 of Cervix: Report of an Unusual Pattern of Endometrial Involvement.

Khalid A Mannan, Meenakshi Rao, Garima Yadav, Taruna Yadav

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of obstetrics and gynaecology of India, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Khalid A MannanDepartment of Pathology and Lab Medicine, AIIMS, Jodhpur, Jodhpur, India.
Meenakshi RaoDepartment of Pathology and Lab Medicine, AIIMS, Jodhpur, Jodhpur, India.
Garima YadavDepartment of Obstetrics and Gynaecology, AIIMS, Jodhpur, Jodhpur, India.
Taruna YadavDepartment of Diagnostic and Interventional Radiology, AIIMS, Jodhpur, Jodhpur, India.
All India Institute of Medical Sciences Jodhpur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microinvasive squamous cell carcinoma (SCC) of the cervix is labeled by the lower anogenital squamous terminology as superficial invasive squamous cell carcinoma (SISCCA). This currently conforms to the T1a1/FIGO IA1 stage, which is defined with a stromal invasion of less than 3 mm in depth (Darragh et al. in Arch Pathol Lab Med 136(10):1266-1297, 2012). Under rare circumstances, these carcinomas can spread laterally to involve the endometrium, which increases the tumor volume and is a significant predictor of outcome. We present a case report of a 60-year-old post-menopausal woman who presented with persistent bleeding and absence of an overt cervical mass on magnetic resonance imaging. She underwent a Wertheim's hysterectomy, and on pathological examination, the cervix revealed a diffuse CIN 3 (Cervical Intraepithelial Neoplasia) with focal microinvasion. In addition, there was extensive superficial spread to the entire endometrium along with focal invasion and lymphovascular space invasion. This presentation is extremely rare, with less than 50 cases reported worldwide (Bagde et al. in J Fam Med Prim Care 10(9):3505, 2021).

Indexed as

CIN 3 cervixCIN 3 endometriumMicroinvasive SCCSuperficial spreading SCC

Identifiers

PMID36457448
PMCPMC9701269
OpenAlexW4283710786

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.