Evidence map›Paper›PMID 36457331›Full record

ArticleFrontiers in public health2022

The clinical and virological features of two children's coinfections with human adenovirus type 7 and human coronavirus-229E virus.

Shelan Liu, An Zhu, Jinren Pan, Lihong Ying, Wanwan Sun, Hanting Wu, Haiying Zhu, Haiyan Lou, Lan Wang, Shuwen Qin and 4 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Shelan LiuDepartment of Infectious Diseases, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
An ZhuDepartment of Pediatrics, Second People's Hospital of Jinyun County, Lishui, China.
Jinren PanDepartment of Infectious Diseases, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Lihong YingDepartment of Infectious Diseases, Jinyun District Center for Disease Control and Prevention, Lishui, China.
Wanwan SunDepartment of Infectious Diseases, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Hanting WuSchool of Public Health, Zhejiang Chinese Medical University, Hangzhou, China.
Haiying ZhuDepartment of Pediatrics, Second People's Hospital of Jinyun County, Lishui, China.
Haiyan LouDepartment of Radiology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Lan WangDepartment of Geriatrics, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Shuwen QinDepartment of Infectious Diseases, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Zhao YuDepartment of Infectious Diseases, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Jian CaiDepartment of Infectious Diseases, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Yin ChenDepartment of Microbiology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Enfu ChenDepartment of Infectious Diseases, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Zhejiang Center for Disease Control and Prevention · CNFirst Affiliated Hospital Zhejiang University · CNXian Yang Central Hospital · CNXian Center for Disease Control and Prevention · CNZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Human adenovirus (HAdV) coinfection with other respiratory viruses is common, but adenovirus infection combined with human coronavirus-229E (HCoV-229E) is very rare. Study design and setting: Clinical manifestations, laboratory examinations, and disease severity were compared between three groups: one coinfected with HAdV-Ad7 and HCoV-229E, one infected only with adenovirus (mono-adenovirus), and one infected only with HCoV-229E (mono-HCoV-229E). Results: From July to August 2019, there were 24 hospitalized children: two were coinfected with HAdV-Ad7 and HCoV-229E, and 21 were infected with a single adenovirus infection. Finally, one 14-year-old boy presented with a high fever, but tested negative for HAdV-Ad7 and HCoV-229E. Additionally, three adult asymptotic cases with HCoV-229E were screened. No significant difference in age was found in the coinfection and mono-adenovirus groups (11 vs. 8 years, Conclusion: HAdV-Ad7 and HCoV-229E coinfection in healthy children may not increase the clinical severity or prolong the clinical course. The specific interaction mechanism between the viruses requires further study.

Indexed as

Adenoviruses, HumanCoinfectionCoronavirusAdolescentAdultChildHospitalsHumansMaleViral Loadcase-control studychildrencoinfectionsHAdV-Ad7human coronavirus-229E(HCoV-229E)respiratory tract infections

Identifiers

PMID36457331
PMCPMC9706225
OpenAlexW4309212046

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.