Evidence map›Paper›PMID 36457292›Full record

ArticlePsychological medicine2023

Intergenerational effects of maternal lifetime stressor exposure on offspring telomere length in Black and White women.

Stefanie E Mayer, Joanna Guan, Jue Lin, Elissa Hamlat, Jordan E Parker, Kristy Brownell, Candice Price, Mahasin Mujahid, A Janet Tomiyama, George M Slavich and 2 more

Open access · greenAbstract read
In one paragraph

Article in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Maternal childhood adversity accelerates epigenetic aging of children.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Stefanie E MayerDepartment of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, CA 94143-0984, USA.
Joanna GuanDepartment of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, CA 94143-0984, USA.
Jue LinDepartment of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94143, USA.
Elissa HamlatDepartment of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, CA 94143-0984, USA.
Jordan E ParkerDepartment of Psychology, University of California, Los Angeles, CA 90095, USA.ORCID 0000-0001-9748-7617
Kristy BrownellSchool of Public Health, University of California Berkeley, Berkeley, CA 94720, USA.
Candice PriceDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, CA 95616, USA.
Mahasin MujahidSchool of Public Health, University of California Berkeley, Berkeley, CA 94720, USA.
A Janet TomiyamaDepartment of Psychology, University of California, Los Angeles, CA 90095, USA.
George M SlavichDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90095, USA.
Barbara A LaraiaSchool of Public Health, University of California Berkeley, Berkeley, CA 94720, USA.
Elissa S EpelDepartment of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, CA 94143-0984, USA.
University of California, San Francisco · USBerkeley Public Health Division · USUniversity of California, Los Angeles · USUniversity of California, Davis · US

Funding

Training In Cardiovascular Physiology & PharmacologyT32HL007444 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ju Chen, Robert Scott Ross · 1985 to 2026
$11.1M
Building Interdisciplinary Research Careers in Womens Health at UC Davis - Administrative SupplementK12HD051958 · NICHD · UNIVERSITY OF CALIFORNIA DAVIS · PI LANE, NANCY E · 2005 to 2023
$9.6M
UCSD PRIDE Faculty Development Program in Cardiovascular SciencesR25HL145817 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Robert Scott Ross, Joann Trejo · 2019 to 2026
$3.3M
Race, Stress and Dysregulated Eating: Maternal to Child Transmission of ObesityR01HD073568 · NICHD · UNIVERSITY OF CALIFORNIA BERKELEY · PI EPEL, ELISSA S., LARAIA, BARBARA A · 2014 to 2018
$2.6M
Early Life Adversity, Cumulative Life Stress, Race, and Cellular Aging in Midlife Women and OffspringR01AG059677 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EPEL, ELISSA S., LARAIA, BARBARA A · 2019 to 2021
$1.7M
Understanding and Reversing the Effects of Early Life Adversity on Midlife Health: Improving Daily Psychological Stress Responses using an Ecological Momentary InterventionR00AG062778 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MAYER, STEFANIE EVA · 2021 to 2023
$747k
Early Life Adversity, Cumulative Life Stress, Race, and Cellular Aging in Midlife Women and OffspringR56AG059677 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EPEL, ELISSA S., LARAIA, BARBARA A · 2018 to 2018
$690k
Neighborhood Environments and Intergenerational Transmission of Cardiovascular HealthR56HL141878 · NHLBI · UNIVERSITY OF CALIFORNIA BERKELEY · PI MUJAHID, MAHASIN S · 2018 to 2018
$520k
Understanding and Reversing the Effects of Early Life Adversity on Midlife Health: Improving Daily Psychological Stress Responses using an Ecological Momentary InterventionK99AG062778 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MAYER, STEFANIE EVA · 2019 to 2020
$311k
NHLBI NIH HHS R25 HL145817NHLBI NIH HHS R56 HL141878NHLBI NIH HHS T32 HL007444NIA NIH HHS K99 AG062778NIA NIH HHS R00 AG062778NIA NIH HHS R01 AG059677NIA NIH HHS R56 AG059677NICHD NIH HHS K12 HD051958NICHD NIH HHS R01 HD073568
6 · The paper itself

Abstract

backgroundAlthough maternal stressor exposure has been associated with shorter telomere length (TL) in offspring, this literature is based largely on White samples. Furthermore, timing of maternal stressors has rarely been examined. Here, we examined how maternal stressors occurring during adolescence, pregnancy, and across the lifespan related to child TL in Black and White mothers.

methodMothers (112 Black; 110 White;

resultsNeither maternal adolescence nor lifespan stressors interacted with race in relation to child TL. In contrast, greater maternal pregnancy stressors were associated with shorter child TL, but this effect was present for children of White but not Black mothers. Moreover, this effect was significant for financial but not social pregnancy stressors. Race-stratified models revealed that greater financial pregnancy stressors predicted shorter telomeres in offspring of White, but not Black mothers.

conclusionsRace and maternal stressors interact and are related to biological aging across generations, but these effects are specific to certain races, stressors, and exposure time periods.

Indexed as

MothersTelomere ShorteningAdolescentAdultBlack or African AmericanChildFemaleHumansIntergenerational RelationsMaternal ExposureMiddle AgedPregnancyProspective StudiesTelomereWhite PeopleYoung AdultCellular agingChronic stressIntergenerational stressPregnancyRaceSTRAIN

Identifiers

PMID36457292
PMCPMC10235210
OpenAlexW4310596041

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.