Evidence map›Paper›PMID 36457286›Full record

ArticleBrain and behavior2023

Automated detection of intracranial large vessel occlusions using Viz.ai software: Experience in a large, integrated stroke network.

Rahul R Karamchandani, Anna Maria Helms, Sagar Satyanarayana, Hongmei Yang, Jonathan D Clemente, Gary Defilipp, Dale Strong, Jeremy B Rhoten, Andrew W Asimos

Open access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 46 citations in OpenAlex.

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  14. Ethical Considerations for Generative Artificial Intelligence in Plastic Surgery.Plastic and reconstructive surgery. Global open · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Rahul R KaramchandaniNeurology, Neurosciences Institute, Atrium Health, Charlotte, North Carolina, USA.ORCID 0000-0002-2111-5523
Anna Maria HelmsNeurosciences Institute, Atrium Health, Charlotte, North Carolina, USA.
Sagar SatyanarayanaInformation and Analytics Services, Atrium Health, Charlotte, North Carolina, USA.
Hongmei YangInformation and Analytics Services, Atrium Health, Charlotte, North Carolina, USA.
Jonathan D ClementeCharlotte Radiology, Neurosciences Institute, Atrium Health, Charlotte, North Carolina, USA.
Gary DefilippCharlotte Radiology, Neurosciences Institute, Atrium Health, Charlotte, North Carolina, USA.
Dale StrongInformation and Analytics Services, Atrium Health, Charlotte, North Carolina, USA.
Jeremy B RhotenNeurosciences Institute, Atrium Health, Charlotte, North Carolina, USA.
Andrew W AsimosEmergency Medicine, Neurosciences Institute, Atrium Health, Charlotte, North Carolina, USA.ORCID 0000-0002-6697-3724
Neurosciences Institute · USAtrium Medical Cente · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeEndovascular thrombectomy is an evidence-based treatment for large vessel occlusion (LVO) stroke. Commercially available artificial intelligence has been designed to detect the presence of an LVO on computed tomography angiogram (CTA). We compared Viz.ai-LVO (San Francisco, CA, USA) to CTA interpretation by board-certified neuroradiologists (NRs) in a large, integrated stroke network.

methodsFrom January 2021 to December 2021, we compared Viz.ai detection of an internal carotid artery (ICA) or middle cerebral artery first segment (MCA-M1) occlusion to the gold standard of CTA interpretation by board-certified NRs for all code stroke CTAs. On a monthly basis, sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) were calculated. Trend analyses were conducted to evaluate for any improvement of LVO detection by the software over time.

results3851 patients met study inclusion criteria, of whom 220 (5.7%) had an ICA or MCA-M1 occlusion per NR. Sensitivity and specificity were 78.2% (95% CI 72%-83%) and 97% (95% CI 96%-98%), respectively. PPV was 61% (95% CI 55%-67%), NPV 99% (95% CI 98%-99%), and accuracy was 95.9% (95% CI 95.3%-96.5%). Neither specificity or sensitivity improved over time in the trend analysis.

conclusionsViz.ai-LVO has high specificity and moderately high sensitivity to detect an ICA or proximal MCA occlusion. The software has the potential to streamline code stroke workflows and may be particularly impactful when emergency access to NRs or vascular neurologists is limited.

Indexed as

Arterial Occlusive DiseasesBrain IschemiaStrokeArtificial IntelligenceCarotid Artery, InternalHumansMiddle Cerebral ArteryRetrospective StudiesSoftwareartificial intelligencelarge vessel occlusionViz.ai

Identifiers

PMID36457286
PMCPMC9847593
OpenAlexW4310542497

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.