Evidence map›Paper›PMID 36457114›Full record

ArticleVirology journal2022

Evaluation of self-administered antigen testing in a college setting.

Sarah C Tinker, Jessica L Prince-Guerra, Kelly Vermandere, Jenna Gettings, Cherie Drenzik, Gary Voccio, Tonia Parrott, Jan Drobeniuc, Tonya Hayden, Stephen Briggs and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Sarah C TinkerCOVID-19 Response Team, Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd NE, Atlanta, GA, 30333, USA. zzu9@cdc.gov.
Jessica L Prince-GuerraCOVID-19 Response Team, Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd NE, Atlanta, GA, 30333, USA.
Kelly VermandereGeorgia Department of Public Health, Atlanta, GA, USA.
Jenna GettingsGeorgia Department of Public Health, Atlanta, GA, USA.
Cherie DrenzikGeorgia Department of Public Health, Atlanta, GA, USA.
Gary VoccioGeorgia Department of Public Health, Atlanta, GA, USA.
Tonia ParrottGeorgia Public Health Laboratory, Atlanta, GA, USA.
Jan DrobeniucCOVID-19 Response Team, Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd NE, Atlanta, GA, 30333, USA.
Tonya HaydenCOVID-19 Response Team, Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd NE, Atlanta, GA, 30333, USA.
Stephen BriggsBerry College, Rome, GA, USA.
Debbie HeidaBerry College, Rome, GA, USA.
Natalie ThornburgCOVID-19 Response Team, Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd NE, Atlanta, GA, 30333, USA.
Lisa C BarriosCOVID-19 Response Team, Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd NE, Atlanta, GA, 30333, USA.
John C NeatherlinCOVID-19 Response Team, Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd NE, Atlanta, GA, 30333, USA.
Sabrina MadniCOVID-19 Response Team, Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd NE, Atlanta, GA, 30333, USA.
Catherine N RasberryCOVID-19 Response Team, Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd NE, Atlanta, GA, 30333, USA.
Kenneth D SwansonCOVID-19 Response Team, Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd NE, Atlanta, GA, 30333, USA.
Azaibi TaminCOVID-19 Response Team, Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd NE, Atlanta, GA, 30333, USA.
Jennifer L HarcourtCOVID-19 Response Team, Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd NE, Atlanta, GA, 30333, USA.
Sandra LesterCOVID-19 Response Team, Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd NE, Atlanta, GA, 30333, USA.
Lydia AthertonCOVID-19 Response Team, Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd NE, Atlanta, GA, 30333, USA.
Margaret A HoneinCOVID-19 Response Team, Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd NE, Atlanta, GA, 30333, USA.

Funding

CDC HHS NU38OT000297
6 · The paper itself

Abstract

backgroundThe objective of our investigation was to better understand barriers to implementation of self-administered antigen screening testing for SARS-CoV-2 at institutions of higher education (IHE).

methodsUsing the Quidel QuickVue At-Home COVID-19 Test, 1347 IHE students and staff were asked to test twice weekly for seven weeks. We assessed seroconversion using baseline and endline serum specimens. Online surveys assessed acceptability.

resultsParticipants reported 9971 self-administered antigen test results. Among participants who were not antibody positive at baseline, the median number of tests reported was eight. Among 324 participants seronegative at baseline, with endline antibody results and ≥ 1 self-administered antigen test results, there were five COVID-19 infections; only one was detected by self-administered antigen test (sensitivity = 20%). Acceptability of self-administered antigen tests was high.

conclusionsTwice-weekly serial self-administered antigen testing in a low prevalence period had low utility in this investigation. Issues of testing fatigue will be important to address in future testing strategies.

Indexed as

COVID-19HumansImmunologic TestsSARS-CoV-2SeroconversionStudentsAdolescentCOVID-19Institutions of higher education (IHE)Quidel QuickVue at-Home OTC COVID-19 TestSARS-CoV-2Self-administered antigen testViral cultureYoung adults

Identifiers

PMID36457114
PMCPMC9713151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.