Evidence map›Paper›PMID 36456929›Full record

ArticleBMC oral health2022

The effect of bone defect size on the 3D accuracy of alveolar bone augmentation performed with additively manufactured patient-specific titanium mesh.

Wei Yang, Dan Chen, Chao Wang, Davide Apicella, Antonio Apicella, Yuanding Huang, Linzhi Li, Lingling Zheng, Ping Ji, Lizhen Wang and 1 more

Abstract read
In one paragraph

Article in BMC oral health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Alveolar Bone Regeneration: Smart Biomaterials and Physical Stimulation.Journal of biomedical materials research. Part B, Applied biomaterials · 2026
    Review
  3. Frontiers in bioengineering and biotechnology · 2026
    Article
  4. [Clinical and histological evaluation of three-dimensional printing individualized titanium mesh for alveolar bone defect repair].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Recent Advances in Scaffolds for Guided Bone Regeneration.Biomimetics (Basel, Switzerland) · 2024
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wei Yang *Stomatological Hospital of Chongqing Medical University, Chongqing, 401147, China.
Dan Chen *Key Laboratory of Biomechanics and Mechanobiology, Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, School of Engineering Medicine, Beihang University, Beijing, 100083, China.
Chao WangStomatological Hospital of Chongqing Medical University, Chongqing, 401147, China. wangchao@hospital.cqmu.edu.cn.ORCID 0000-0001-7792-9887
Davide ApicellaMarrelly Health, calabrodental hospital, 88900, Crotone, Italy.
Antonio ApicellaAdvanced Materials Lab, Department of Architecture and Industrial Design, University of Campania, 81031, Aversa, Italy.
Yuanding HuangStomatological Hospital of Chongqing Medical University, Chongqing, 401147, China.
Linzhi LiStomatological Hospital of Chongqing Medical University, Chongqing, 401147, China.
Lingling ZhengKey Laboratory of Biomechanics and Mechanobiology, Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, School of Engineering Medicine, Beihang University, Beijing, 100083, China.
Ping JiStomatological Hospital of Chongqing Medical University, Chongqing, 401147, China.
Lizhen WangKey Laboratory of Biomechanics and Mechanobiology, Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, School of Engineering Medicine, Beihang University, Beijing, 100083, China.
Yubo FanKey Laboratory of Biomechanics and Mechanobiology, Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, School of Engineering Medicine, Beihang University, Beijing, 100083, China.

Funding

National Natural Science Foundation of China 11872135National Natural Science Foundation of China 12172034National Natural Science Foundation of China U20A20390the National Natural Science Foundation of China 12072055the Natural Science Foundation of Beijing L212063
6 · The paper itself

Abstract

objectiveAdditively manufactured (3D-printed) titanium meshes have been adopted in the dental field as non-resorbable membranes for guided bone regeneration (GBR) surgery. However, according to previous studies, inaccuracies between planned and created bone volume and contour are common, and many reasons have been speculated to affect its accuracy. The size of the alveolar bone defect can significantly increase patient-specific titanium mesh design and surgical difficulty. Therefore, this study aimed to analyze and investigate the effect of bone defect size on the 3D accuracy of alveolar bone augmentation performed with additively manufactured patient-specific titanium meshes.

methodsTwenty 3D-printed patient-specific titanium mesh GBR surgery cases were enrolled, in which 10 cases were minor bone defect/augmentation (the planned bone augmentation surface area is less than or equal to 150 mm

resultsThere was no significant difference in the 3D deviation distance of bone augmentation between the minor bone defect/augmentation group and the major one. The contour lines of planned-CAD models in two groups were basically consistent with the contour lines after GBR surgery, and both covered the preoperative contour lines. Moreover, the exposure rate of titanium mesh in the minor bone defect/augmentation group was slightly lower than the major one.

conclusionIt can be concluded that the size of the bone defect has no significant effect on the 3D accuracy of alveolar bone augmentation performed with the additively manufactured patient-specific titanium mesh.

Indexed as

AnodontiaDental ImplantsMalocclusionTooth LossHumansSurgical MeshTitaniumDental ImplantsTitaniumAdditively manufactured patient-specific titanium meshAlveolar bone defectsBone augmentationCAD/CAMDigital registration

Identifiers

PMID36456929
PMCPMC9713982

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.