ArticleBMC neurology2022
Determinants of post-stroke depression among stroke survivors at University of Gondar Hospital, Northwest Ethiopia: a case-control study.
Article in BMC neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Post-Stroke Depression and Determinants in Ethiopia; A Systematic Review and Meta-Analysis.International journal of methods in psychiatric research · 2026Pooled it
- Exploring the occurence and risk factors of post-stroke depression among stroke survivors in Africa: a comprehensive systematic review and meta-analysis.BMC public health · 2025Pooled it
- Prevalence and associated factors of post-stroke depression in Africa: a systematic review and meta-analysis.BMC neurology · 2024Pooled it
- Poststroke depression severity among older Nigerian adults with confirmed poststroke disabilities: a multisite hospital-based cross-sectional study.BMJ public health · 2026Article
- Posttraumatic stress disorder and associated factors among stroke survivors in Northwest Ethiopia.Discover mental health · 2025Article
- Antimicrobial susceptibility patterns and associated risk factors of bacterial isolate among urinary tract infection suspected patients at University of Gondar Comprehensive Specialized Hospital North west Ethiopia.BMC infectious diseases · 2025Article
- Post-stroke depression prevalence and associated factors at Hawassa University Hospital, Ethiopia: A prospective cross-sectional study.PCN reports : psychiatry and clinical neurosciences · 2025Article
- Cardiac history and post-stroke depression association in Chinese stroke survivors: a cross sectional study.Scientific reports · 2025Article
- A higher burden of post-stroke depression and anxiety and their predictors among stroke survivors in the Amhara Regional State, Ethiopia, in 2024: a prospective multicenter study.Frontiers in psychiatry · 2025Article
- Article
- Prevalence and network structure of depression and its association with quality of life among older stroke survivors: findings from a national survey in China.General psychiatry · 2025Article
- Prevalence and associated factors of post-stroke depression among patients on follow-up at medical referral clinics of Bahir Dar city public specialized hospitals.BMC neurology · 2024Article
- Drivers of Chronic Pathology Following Ischemic Stroke: A Descriptive Review.Cellular and molecular neurobiology · 2023Review
- Predictive microbial feature analysis in patients with depression after acute ischemic stroke.Frontiers in aging neuroscience · 2023Article
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6 authors at 1 institution in 1 country.
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Abstract
backgroundStroke is one of the most common causes of disability among adults. Post-stroke depression (PSD) is a frequent neuropsychiatric complication in stroke patients. Despite the increasing prevalence of stroke, there is a paucity of data on PSD and its determinants among stroke survivors in developing countries like Ethiopia. We aim to assess the factors associated with PSD in survivors of stroke.
methodA hospital-based unmatched case-control study was conducted during the period of February to July 2020 at University of Gondar Hospital among stroke survivors. Study subjects were recruited consecutively. Socio-demographic and clinical data were obtained from patients' interviews and medical record reviews. A diagnosis of PSD was made using the Patient Health Questionnaire (PHQ-9). EpiData version 3.1 was used to enter data, and SPSS version 26 was used to analyze it. Bivariate and multivariate logistic regressions were fitted to identify associated variables. The adjusted odds ratio (AOR) with 95% confidence interval (CI) and p-value 0.05 were used to determine the significance of the association.
resultA total of 240 stroke survivors were included in the study (80 cases and 160 controls). The mean age was 60.8 years (SD ± 14.3) with an equal sex distribution. Variables statistically associated with PSD were male gender (AOR = 3.5, 95% CI: 1.64-7.46 C, P-value = 0.001), subcortical location of the largest lesion (AOR = 2.42, 95% CI: 1.06-5.56, p-value = 0.036), severity of the stroke (AOR = 52.34, 95% CI:10.64-256.87, p-value = 0.000), physical disability (AOR = 5.85. 95% CI:1.94-17.65, p-value = 0.002), previous history of stroke or transient ischemic attack (AOR = 5.90, 95% CI:2.04-17.10, p-value = 0.001) and ischemic heart disease (AOR = 9.97, 95% CI:3.4-29.22, p-value = 0.000).
conclusionImportant factors in the occurrence of PSD in this study include prior history of stroke, physical disability, severity of the stroke, subcortical location of the lesion, male gender, and ischemic heart disease. Stroke patients with such factors need routine screening for PSD, particularly in LMICs where there is uncoordinated post-stroke care, a shortage of neurologists and mental health practitioners.
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