SynthesisNeuropsychology review2023
Association of Self-Reported Psychological Stress with Cognitive Decline: A Systematic Review.
Synthesis in Neuropsychology review, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 36 citations in OpenAlex.
- Association of psychosocial stress with altered functional connectivity of large-scale brain networks in aging adults.Cognitive, affective & behavioral neuroscience · 2026Article
- Loneliness is associated with cognitive impairment in patients with schizophrenia: the mediating roles of sleep quality and anxiety.European archives of psychiatry and clinical neuroscience · 2026Article
- [Modifiable risk and protective factors for dementia: an overview of established and emerging evidence].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2026Review
- Independent trajectories of cognitive function and daily events across 9 years during midlife and old age.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Stressful Life Event Exposure Is Associated with Combined Physical and Cognitive Decline in Older Adults.Gerontology · 2026Article
- Daily life experiences of cognitive changes in community-dwelling older adults with subjective cognitive decline: A qualitative study.Journal of Alzheimer's disease : JAD · 2026Article
- Assessing relationships between cognition, sleep, and mental health in pediatric patients with chronic pain.The journal of pain · 2026Observational
- Drought and cognitive function in older adults: results from the Mexican health and aging study.Environment international · 2026Article
- Neuroprotective Effects of C-Phycocyanin in Chronic Unpredictable Mild Stress-Exposed Rats: Regulation of Neuroinflammation and CREB/BDNF Signaling.Neurochemical research · 2026Article
- The influence mechanism of mindfulness training on college students' psychological stress regulation: a mediation model with moderating effect.Frontiers in public health · 2026Article
- Ethnic Disparities in Physical, Mental, and Cognitive Health During the COVID-19 Pandemic: a Snapshot of Metro-Detroit.Journal of racial and ethnic health disparities · 2025Article
- Mental health of older adults in humanitarian settings in low- and middle-income countries: a retrospective analysis from Médecins sans Frontières-supported mental health services, 2019-2024.BMJ global health · 2025Article
- Association between mild cognitive impairment and sleep quality in patients with chronic heart failure: a cross-sectional study.Frontiers in psychiatry · 2025Article
- Personality and neuropsychiatric symptoms in individuals diagnosed with long COVID.BMC infectious diseases · 2024Article
- Oral issues and childhood stress in eight-to-ten-year-old schoolchildren: a case-control study.Clinical oral investigations · 2024Article
- A Prospective Study on Neural Biomarkers in Patients with Long-COVID Symptoms.Journal of personalized medicine · 2024Article
- Relationship between domain-specific physical activity and cognitive function in older adults - findings from NHANES 2011-2014.Frontiers in public health · 2024Article
- Associations of Perceived Stress and Psychological Resilience With Cognition and a Modifiable Dementia Risk Score in Middle-Aged Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023Article
- Cumulative Stress Exposure and Cognitive Function Among Older Adults: The Moderating Role of a Healthy Lifestyle.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023Article
- Exploring the Potential Association Between Self-Reported Psychological Stress and Cerebrospinal Fluid Biomarkers of Alzheimer's Disease in Midlife: A Cross-Sectional Study.Journal of Alzheimer's disease reports · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Psychological stress is a potential modifiable risk factor for cognitive decline. However, the extent to which self-reported psychological stress is differentially associated with decline in specific cognitive domains remains unclear. Differences may be due to heterogeneity in the aspects of psychological stress investigated, for example, neuroticism (which is linked to vulnerability to stress), perceived stress, or exposure to stressful life events. This review aims to establish the associations between these aspects of self-reported psychological stress and cognitive decline. PsychINFO, Embase and MEDLINE were searched from database inception to September 2021. Studies were included if they were observational, prospective, and if they investigated the association between self-reported psychological stress and cognitive decline in adults with a minimum mean age of 40 years at baseline. Thirty studies satisfied the inclusion criteria, with most examining neuroticism (n = 17) as a predictor of cognitive decline. Fewer examined perceived stress (n = 7) or stressful life events (n = 6). There was evidence of an association between neuroticism and cognitive decline, particularly in the domain of memory. Similarly, across studies, perceived stress was also associated with memory decline. Research investigating the relationship between stressful life events and cognitive decline had fewer outcomes to interpret. Overall, the findings highlight that memory may be particularly susceptible to high levels of neuroticism and perceived stress. We identified a lack of research into some cognitive domains, such as executive function, which should be addressed by future studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.