Evidence map›Paper›PMID 36456741›Full record

ArticleBiological trace element research2023

The Role of Reduced Glutathione on the Activity of Adenosine Deaminase, Antioxidative System, and Aluminum and Zinc Levels in Experimental Aluminum Toxicity.

Onur Atakisi, Kezban Yildiz Dalginli, Canan Gulmez, Destan Kalacay, Emine Atakisi, Taasilkan Toktamamatovna Zhumabaeva, Tunay Kontaş Aşkar, Ruken Esra Demirdogen

Abstract read
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In one paragraph

Article in Biological trace element research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Onur AtakisiDepartment of Chemistry, Faculty of Science and Letter, Kafkas University, Kars, Turkey. onuratakisi@hotmail.com.ORCID http://orcid.org/0000-0003-1183-6076
Kezban Yildiz DalginliDepartment of Chemistry and Chemical Processing Technologies Kars Vocational School, Kafkas University, Kars, Turkey.ORCID http://orcid.org/0000-0002-1483-348X
Canan GulmezDepartment of Pharmacy Services, Tuzluca Vocational School, Igdir University, Igdir, Turkey.ORCID http://orcid.org/0000-0003-3253-1407
Destan KalacayDepartment of Chemistry and Chemical Processing Technologies Kars Vocational School, Kafkas University, Kars, Turkey.ORCID http://orcid.org/0000-0002-3921-5549
Emine AtakisiFaculty of Veterinary Medicine Department of Biochemistry, Kafkas University, Kars, Turkey.ORCID http://orcid.org/0000-0002-5685-1870
Taasilkan Toktamamatovna ZhumabaevaDepartment of Biology Medical Institute, Osh State University, Osh, Kyrgyzstan.
Tunay Kontaş AşkarDepartment of Dietetics and Nutrition, Faculty of Health Sciences, Çankırı Karatekin University, Çankırı, Turkey.ORCID http://orcid.org/0000-0002-1121-8799
Ruken Esra DemirdogenDeptartments of Chemistry Faculty of Science, Çankırı Karatekin University, Çankırı, Turkey.ORCID http://orcid.org/0000-0003-2391-3454
Kafkas University · TRÇankırı Karatekin University · TRIğdır Üniversitesi · TROsh State University · KG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aluminum (Al) is one of the most abundant element in the world. But aluminum exposure and accumulation causes serious diseases, related with free radicals. Reduced glutathione (GSH) is a tripeptide with intracellular antioxidant effects. This study aimed to investigate the role of GSH on adenosine deaminase (ADA), antioxidant system, and aluminum and zinc (Zn) levels in acute aluminum toxicity. In this study, Sprague-Dawley rats (n = 32) were used. The rats were divided into four equal groups (n = 8). Group I received 0.5 mL intraperitoneal injection of 0.9% saline solution (NaCI), Group II received single-dose AlCI

Indexed as

AntioxidantsGlutathioneAdenosine DeaminaseAluminumAnimalsOxidantsOxidative StressRatsRats, Sprague-DawleyZincAdenosine DeaminaseAluminumAntioxidantsGlutathioneOxidantsZincAdenosine deaminaseAluminumAntioxidative systemZinc

Identifiers

PMID36456741
OpenAlexW4310600483

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.