Evidence map›Paper›PMID 36455558›Full record

ArticleCell2022

Genome-wide data from medieval German Jews show that the Ashkenazi founder event pre-dated the 14

Shamam Waldman, Daniel Backenroth, Éadaoin Harney, Stefan Flohr, Nadia C Neff, Gina M Buckley, Hila Fridman, Ali Akbari, Nadin Rohland, Swapan Mallick and 22 more

Open access · hybridAbstract read
In one paragraph

Article in Cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 60 citations in OpenAlex.

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  10. Unveiling ancestral threads: Exploring CCR5 ∆32 mutation frequencies in Colombian populations for HIV/AIDS therapeutics.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2024
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  18. Familial dysautonomia.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors at 16 institutions in 5 countries.

Shamam WaldmanBraun School of Public Health and Community Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
Daniel BackenrothBraun School of Public Health and Community Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
Éadaoin HarneyDepartment of Human Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.
Stefan FlohrDepartment of Biology, University of Hildesheim, 31141 Hildesheim, Germany.
Nadia C NeffDepartment Anthropology, University of New Mexico, Albuquerque, NM 87131, USA; Center for Stable Isotopes, University of New Mexico, Albuquerque, NM 87106, USA.
Gina M BuckleyResearch Reactor Center, University of Missouri, Columbia, MO 65211, USA.
Hila FridmanBraun School of Public Health and Community Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel; Medical Genetics Institute, Shaare Zedek Medical Center, Jerusalem 9103102, Israel; Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112001, Israel.
Ali AkbariDepartment of Human Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Nadin RohlandDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Swapan MallickDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.
Iñigo OlaldeDepartment of Human Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA; Department of Zoology and Animal Cell Biology, University of the Basque Country UPV/EHU, 01006 Vitoria-Gasteiz, Spain; Ikerbasque-Basque Foundation of Science, 48009 Bilbao, Spain.
Leo CooperIndependent Scholar, Kalamazoo, MI 49008, USA.
Ariel LomesBraun School of Public Health and Community Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
Joshua LipsonIndependent Scholar, New York, NY 10027, USA.
Jorge Cano NistalFaculty of Biotechnology and Food Engineering, Technion - Israel Institute of Technology, Haifa 3200003, Israel.
Jin YuDepartment of Psychiatry, Division of Research, The Zucker Hillside Hospital Division of Northwell Health, Glen Oaks, NY 11004, USA.
Nir BarzilaiDepartments of Medicine and Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Inga PeterDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Gil AtzmonDepartments of Medicine and Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Faculty of Natural Sciences, University of Haifa, Haifa 3498838, Israel.
Harry OstrerDepartment of Pathology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Todd LenczDepartment of Psychiatry, Division of Research, The Zucker Hillside Hospital Division of Northwell Health, Glen Oaks, NY 11004, USA; Departments of Psychiatry and Molecular Medicine, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11550, USA; Institute for Behavioral Science, The Feinstein Institutes for Medical Research, Manhasset, NY 11030, USA.
Yosef E MaruvkaFaculty of Biotechnology and Food Engineering, Technion - Israel Institute of Technology, Haifa 3200003, Israel.
Maike LämmerhirtDepartment of Medieval History, University of Erfurt, 99089 Erfurt, Germany.
Alexander BeiderIndependent Scholar, 92370 Chaville, France.
Leonard V RutgersDepartment of History and Art History, Utrecht University, Utrecht 3512 BS, the Netherlands.
Virginie RensonResearch Reactor Center, University of Missouri, Columbia, MO 65211, USA.
Keith M PruferDepartment Anthropology, University of New Mexico, Albuquerque, NM 87131, USA; Center for Stable Isotopes, University of New Mexico, Albuquerque, NM 87106, USA.
Stephan SchiffelsDepartment of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, 04103 Leipzig, Germany.
Harald RingbauerDepartment of Human Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA; Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, 04103 Leipzig, Germany.
Karin SczechWorld Heritage Coordinator, City of Erfurt, 99084 Erfurt, Germany.
Shai CarmiBraun School of Public Health and Community Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel. Electronic address: shai.carmi@huji.ac.il.
David ReichDepartment of Human Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA. Electronic address: reich@genetics.med.harvard.edu.
Hebrew University of Jerusalem · ILBroad Institute · USAlbert Einstein College of Medicine · USHarvard University · USNorthwell Health · USTechnion – Israel Institute of Technology · ILUniversity of Missouri · USUniversity of New Mexico · USFilm Independent · USIcahn School of Medicine at Mount Sinai · USIkerbasque · ESMax Planck Institute for Evolutionary Anthropology · DEThüringer Aufbaubank · DEUniversity of Erfurt · DEUniversity of Hildesheim · DEUtrecht University · NL

Funding

Solving ascertainment bias in ancient DNA using Ultima Genomics sequencingR01HG012287 · NHGRI · HARVARD MEDICAL SCHOOL · PI REICH, DAVID E · 2021 to 2025
$2.7M
Population mixture in evolutionary and medical geneticsR01GM100233 · NIGMS · HARVARD MEDICAL SCHOOL · PI PATTERSON, NICK J, REICH, DAVID E · 2012 to 2019
$2.7M
NHGRI NIH HHS R01 HG012287NIGMS NIH HHS R01 GM100233
6 · The paper itself

Abstract

We report genome-wide data from 33 Ashkenazi Jews (AJ), dated to the 14

Indexed as

JewsWhite PeopleGenetics, PopulationGenome, HumanHumansadmixtureancient DNAAshkenazi Jewsdemographic inferencefounder eventIBD sharingmitochondrial DNApathogenic variantspopulation structureruns of homozygosity

Identifiers

PMID36455558
PMCPMC9793425
OpenAlexW4313279459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.