Evidence map›Paper›PMID 36455156›Full record

ArticleACS infectious diseases2023

Sialosides Containing 7-

Anoopjit Singh Kooner, Yue Yuan, Hai Yu, Hyeog Kang, Laura Klenow, Robert Daniels, Xi Chen

Open access · hybridAbstract read
In one paragraph

Article in ACS infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anoopjit Singh KoonerDepartment of Chemistry, University of California, One Shields Avenue, Davis, California 95616, United States.
Yue YuanDepartment of Chemistry, University of California, One Shields Avenue, Davis, California 95616, United States.
Hai YuDepartment of Chemistry, University of California, One Shields Avenue, Davis, California 95616, United States.ORCID 0000-0002-4378-0532
Hyeog KangDivision of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland 20993, United States.
Laura KlenowDivision of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland 20993, United States.
Robert DanielsDivision of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland 20993, United States.ORCID 0000-0002-5988-2920
Xi ChenDepartment of Chemistry, University of California, One Shields Avenue, Davis, California 95616, United States.ORCID 0000-0002-3160-614X
University of California, Davis · USCenter for Biologics Evaluation and Research · US

Funding

Supplement: Exploring the biology of O-acetyl sialic acids using stable synthetic mimicsR01AI130684 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHEN, XI, VARKI, AJIT P · 2017 to 2020
$2.3M
Chemoenzymatic synthesis of bacterial nonulosonic acids and glycansR01GM141324 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHEN, XI · 2021 to 2024
$1.2M
Acquisition of a Q-Exactive Plus Mass SpectrometerS10OD025271 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JEWELL, WILLIAM T · 2019 to 2019
$486k
NIAID NIH HHS R01 AI130684NIGMS NIH HHS R01 GM141324NIH HHS S10 OD025271
6 · The paper itself

Abstract

Sialidases or neuraminidases are sialic-acid-cleaving enzymes that are expressed by a broad spectrum of organisms, including pathogens. In nature, sialic acids are monosaccharides with diverse structural variations, but the lack of novel probes has made it difficult to determine how sialic acid modifications impact the recognition by sialidases. Here, we used a chemoenzymatic synthon strategy to generate a set of α2-3- and α2-6-linked sialoside probes that contain 7-

Indexed as

Influenza A virusInfluenza A Virus, H1N1 SubtypeHumansInfluenza A Virus, H3N2 SubtypeN-Acetylneuraminic AcidNeuraminidaseSialic AcidsN-Acetylneuraminic AcidNeuraminidaseSialic Acidscarbohydratechemoenzymatic synthesisinfluenza A virus neuraminidaseN-acetyl analogueO-acetyl sialic acidsialidase

Identifiers

PMID36455156
PMCPMC9840695
OpenAlexW4310504336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.