ArticlePloS one2022
The effect of cold-knife conization on pregnancy outcomes in patients with cervical lesions.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 20 citations in OpenAlex.
- Association between cervical conization and pregnancy outcomes: A nationwide population-based cohort study.PloS one · 2026Article
- Hysteroscopic Cold Knife Separation Combined with Autologous Platelet Rich Plasma for the Treatment of Intrauterine Adhesions: A Comparative Study.International journal of women's health · 2026Article
- Intraepithelial lesions of the uterine cervix during pregnancy: reaffirming the safety of conservative management.Gynecologic oncology reports · 2025Article
- Factors affecting obstetric outcomes in patients who underwent cold-knife and loop electrosurgical excision procedure conization due to cervical intraepithelial neoplasia 2 or cervical intraepithelial neoplasia 3Journal of the Turkish German Gynecological Association · 2024Article
- LncRNA WWTR1-AS1 upregulates Notch3 through miR-136 to increase cancer cell stemness in cervical squamous cell carcinoma.BMC women's health · 2024Article
- Establishment and validation of a prognostic model for premature rupture of membranes and preterm delivery in pregnant women after cervical conization.American journal of translational research · 2024Article
- Differential Analysis of Pregnancy Outcomes After Treatment of HIFU and LEEP in Patients with Cervical High-Grade Squamous Intraepithelial Lesions.International journal of women's health · 2024Article
- The Effect of Cervical Cold-Knife Conization (CKC) on HPV Infection in Patients with High-Grade Cervical Intraepithelial Neoplasia: A Retrospective Study.International journal of women's health · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo analyze the pregnancy outcomes of patients with cervical lesions treated by cold-knife conization (CKC).
methodsClinical data of healthy pregnant women and pregnant women who underwent CKC in Dalian Women and Children's Medical Group from March 2010 to December 2019 were retrospectively analyzed. These patients were divided into a CKC group and a control group according to inclusion and exclusion criteria. Statistical methods were used to compare pregnancy and delivery outcomes between the two groups.
resultsThere were 400 patients in CKC group and control group, with 200 patients in each. There was no significant difference in the mode of delivery, abortion, ectopic pregnancy, in-hospital perinatal management, and cervical cerclage between the CKC group and the control group (P>0.05). The rates of preterm delivery, premature rupture of membranes, cesarean section, and neonatal admission in the CKC group were higher than those in the control group (P<0.05). In the CKC group, the incidence of premature rupture of membranes within six months postoperatively was higher than that after six months (P<0.05). The incidences of preterm delivery and premature rupture of membranes were not completely consistent in different conization ranges (P<0.05).
conclusionCKC increases the incidence of preterm delivery, premature rupture of membranes, and neonatal adverse outcomes. Conization height can predict the occurrence of preterm delivery. Delaying pregnancy after surgery can reduce the incidence of adverse outcomes during the perinatal period.
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