Evidence map›Paper›PMID 36454870›Full record

ArticlePloS one2022

The social construction of genomics and genetic analysis in ocular diseases in Ibadan, South-western Nigeria.

Olusola Olawoye, Kabiru K Salami, Abolaji Azeez, Precious Adebola, Tarela Sarimiye, John Imaledo, Tony Realini, Michael A Hauser, Adeyinka Ashaye

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Olusola OlawoyeDepartment of Ophthalmology, Faculty of Clinical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Kabiru K SalamiDepartment of Sociology, Faculty of the Social Sciences, University of Ibadan, Ibadan, Nigeria.ORCID 0000-0001-8874-0131
Abolaji AzeezDepartment of Sociology, Faculty of the Social Sciences, University of Ibadan, Ibadan, Nigeria.
Precious AdebolaDepartment of Ophthalmology, University College Hospital Ibadan, Ibadan, Nigeria.ORCID 0000-0002-4538-893X
Tarela SarimiyeDepartment of Ophthalmology, Faculty of Clinical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
John ImaledoDepartment of Health Promotion and Education, Faculty of Public Health, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Tony RealiniDepartment of Ophthalmology and Visual Sciences, School of Medicine, West Virginia University, Morgantown, West Virginia, United States of America.
Michael A HauserDepartment of Medicine, Duke University School of Medicine, Duke University, Durham, North Carolina, United States of America.
Adeyinka AshayeDepartment of Ophthalmology, Faculty of Clinical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.

Funding

Project 3_The GambiaU54HG009826 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI ASHAYE, ADEYINKA O · 2017 to 2021
$3.8M
NHGRI NIH HHS U54 HG009826
6 · The paper itself

Abstract

Genomics, an emerging field to improve public health practice, has potential benefits to understanding ocular diseases. This study explored the social construction of genomics in ocular diseases in the blind community in Ibadan, Nigeria, through two focus group discussions and twelve in-depth interview sessions conducted among people living with ocular disorders. The data were thematic and content-analysed. Although the participants had limited knowledge about ocular diseases, genomics, and their nexus, they maintained a positive attitude toward its potential benefits. This informed their willingness to participate in genomics testing for ocular diseases. The participants preferred saliva-based sample collection over blood-based, and expressed concern for the procedure and accrued benefits of genomics studies. Thus, public sensitisation about ocular diseases and client-centred genomics testing procedures should be engendered.

Indexed as

EyeGenetic TestingFaceGenomicsHumansNigeria

Identifiers

PMID36454870
PMCPMC9714877

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.