Evidence map›Paper›PMID 36454481›Full record

ArticleForensic toxicology2022

Synthetic cannabinoid receptor agonists profile in infused papers seized in Brazilian prisons.

Taís B Rodrigues, Mônica P Souza, Lilian de Melo Barbosa, Júlio de Carvalho Ponce, Luiz F Neves Júnior, Maurício Yonamine, Jose Luiz Costa

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In one paragraph

Article in Forensic toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. The dilemma of new psychoactive substances: A growing threat.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Taís B RodriguesCampinas Poison Control Center, University of Campinas, Campinas, SP 13083-859, Brazil.
Mônica P SouzaNational Institute of Criminalistics, Brazilian Federal Police, Brasília, DF 70610-200, Brazil.
Lilian de Melo BarbosaSuperintendence of the Technical-Scientific Police, Institute of Criminalistics, São Paulo, SP 05507-060, Brazil.
Júlio de Carvalho PonceSuperintendence of the Technical-Scientific Police, Institute of Criminalistics, São Paulo, SP 05507-060, Brazil.
Luiz F Neves JúniorSuperintendence of the Technical-Scientific Police, Institute of Criminalistics, São Paulo, SP 05507-060, Brazil.
Maurício YonamineSchool of Pharmaceutical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil.
Jose Luiz CostaCampinas Poison Control Center, University of Campinas, Campinas, SP 13083-859, Brazil. jose.jlc@fcf.unicamp.br.ORCID 0000-0001-9607-3391
Federal Police of Brazil · BRUniversidade Estadual de Campinas (UNICAMP) · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSynthetic cannabinoid receptor agonists (SCRAs) are a class of varied compounds that mimic the effects of natural cannabinoids found in cannabis. Because they have a wide range of diverse structures, they vary widely in their potency. The abuse of new psychoactive substances (NPS) in prisons was reported in many European countries and in the USA. In the present study, we have described the identification of SCRAs in 56 infused paper sheet samples, seized mainly in Brazilian prisons between 2016 and 2020.

methodsThe materials were seized by local or federal law enforcement and analyzed by São Paulo State Police or Brazilian Federal Police using gas chromatography-mass spectrometry, attenuated total reflection-Fourier transform infrared spectroscopy, liquid chromatography-high-resolution mass spectrometry or nuclear magnetic resonance spectrometry.

resultsMost of these samples (87.5%) were seized in 2019-2020; seven different SCRAs were identified in samples, and the most frequently identified substances were MDMB-4en-PINACA (23.6%) and 5F-MDMB-PICA (36.4%), the newest SCRAs emerging recently.

conclusionsAs observed in Europe and the USA, Brazil also shows the prevalence of indazole-3-carboxamides and indole-3-carboxamides among SCRAs seizures in the prison system. This phenomenon is spreading all over the world at this moment. These data on the prevalence could help to alert judicial authorities to shutting down the introduction of NPS, including SCRAs, into prisons to ensure safety and security for avoiding health risks of prisoners and staff, leading to positive effects in this population. To our knowledge, this is the first demonstration of SCRAs smuggling into prisons in Latin America.

Indexed as

Cannabinoid Receptor AgonistsPrisonersBrazilCannabinoidsHumansPrisonsCannabinoid Receptor AgonistsCannabinoidsMDMB-4en-PINACA5F-MDMB-PICAAbuse in prisonsMDMB-4en-PINACANew psychoactive substances (NPS)Synthetic cannabinoid receptor agonists

Identifiers

PMID36454481
OpenAlexW3173340660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.