Evidence map›Paper›PMID 36454306›Full record

ArticleArchives of orthopaedic and trauma surgery2023

Long-term analysis of chronic pain associated with lower extremity injuries.

Thomas Rauer, Eva Friedl, Jamison G Gamble, Boris A Zelle, Hans-Christoph Pape, Roman Pfeifer

Open access · hybridAbstract read
In one paragraph

Article in Archives of orthopaedic and trauma surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Physical functionality two years after major trauma: predictors from a single center cohort study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Extensive Periosteal Injury During Fracture Induces Long-Term Pain in Mice.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Thomas RauerDepartment of Trauma Surgery, University Hospital Zurich, 8091, Zurich, Switzerland. Thomas.Rauer@usz.ch.ORCID http://orcid.org/0000-0003-4775-1103
Eva FriedlDepartment of Trauma Surgery, University Hospital Zurich, 8091, Zurich, Switzerland.
Jamison G GambleSt. George's University School of Medicine, St. George, Grenada.
Boris A ZelleDepartment of Orthopedics, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Hans-Christoph PapeDepartment of Trauma Surgery, University Hospital Zurich, 8091, Zurich, Switzerland.
Roman PfeiferDepartment of Trauma Surgery, University Hospital Zurich, 8091, Zurich, Switzerland.
University Hospital of Zurich · CHSt. George's University · GDThe University of Texas Health Science Center at San Antonio · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe main objective of this study is to examine chronic pain and limping in relation to lower extremity and pelvic fracture location in addition to fracture combinations if multiple fractures are present on the same leg that have not been previously reported. We hypothesize that fracture pattern and location of lower extremity and pelvis fractures of multiple injured patients influence their long-term pain outcome. MATERIALS AND

methodsRetrospective cohort study. Patients with treated multiple lower limb and pelvic fractures at a level 1 trauma center and followed up for at least 10 years postinjury were assessed. Lower leg pain subdivided into persistent, load-dependent and intermittent pain, as well as limping were recorded by using self-administered patient questionnaires and standardized physical examinations performed by a trauma surgeon. Descriptive statistics were used to present comparative measurements between groups.

resultsFifty-seven percent of patients (n = 301) showed chronic lower limb pain 10 years postinjury. Ten percent of all patients with chronic pain displayed persistent pain, and here the most common fracture combination was tibial shaft fractures in combination with femoral shaft or proximal tibial fractures (13%). One hundred fifty-one patients reported load-dependent pain, with the most common fracture combinations being fractures of the foot in combination with femoral shaft fractures or distal tibial fractures (11%). One hundred twenty patients reported intermittent pain, with the most common fracture combinations involving the shaft of the tibia with either the femoral shaft or distal tibia (9%). Two hundred fifteen patients showed a persistent limp, and here the most common fractures were fractures of the femoral shaft (19%), tibial shaft (17%), and pelvis (15%).

conclusionsIn multiple injured patients with lower extremity injuries, the combination of fractures and their location are critical factors in long-term outcome. Patients with chronic persistent or load-dependent pain often had underlying femoral shaft fractures in combination with joint fractures.

Indexed as

Chronic PainFemoral FracturesHumansLegRetrospective StudiesTibial FracturesAcetabulumChronic painLong-term outcomeLower limbMultiple injuriesPolytrauma

Identifiers

PMID36454306
PMCPMC10293374
OpenAlexW4310566399

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.