Evidence map›Paper›PMID 36453788›Full record

ArticleUlusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES2022

An effective and reliable marker in gradıng the severity of acute cholecystitis: Increased immature granulocyte percentage.

Yılmaz Ünal, Salih Tuncal, Berkay Küçük, Aziz Mutlu Barlas, Saygın Altıner, Recep Balık, Seyit Murat Aydın, Abdullah Senlikci, Mevlüt Recep Pekcici

Open access · hybridAbstract read
In one paragraph

Article in Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Nucleated Red Blood Cells for Predicting Mortality in Intensive Care Unit Patients With Sepsis.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
  4. Article
  5. The role of infectious parameters in the early prediction of complicated colonic diverticulitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Yılmaz ÜnalDepartment of General Surgery, University of Health Sciences Ankara Training and Research Hospital, Ankara-Türkiye.
Salih TuncalDepartment of General Surgery, University of Health Sciences Ankara Training and Research Hospital, Ankara-Türkiye.
Berkay KüçükDepartment of Intensive Care, University of Health Sciences Ankara City Hospital, Ankara-Türkiye.
Aziz Mutlu BarlasDepartment of General Surgery, University of Health Sciences Ankara Training and Research Hospital, Ankara-Türkiye.
Saygın AltınerDepartment of General Surgery, University of Health Sciences Ankara Training and Research Hospital, Ankara-Türkiye.
Recep BalıkDepartment of Infectious Diseases and Clinical Microbiology, University of Health Sciences Haydarpaşa Numune Training and Research Hospital, İstanbul-Türkiye.
Seyit Murat AydınDepartment of General Surgery, University of Health Sciences Ankara Training and Research Hospital, Ankara-Türkiye.
Abdullah SenlikciDepartment of General Surgery, University of Health Sciences Ankara Training and Research Hospital, Ankara-Türkiye.
Mevlüt Recep PekciciDepartment of General Surgery, University of Health Sciences Ankara Training and Research Hospital, Ankara-Türkiye.
University of Health Science · KH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute cholecystitis (AC) is an acute inflammatory disease of gallbladder and it is one of the most common causes of acute abdominal pain. Determining the severity of AC at hospital admission is extremely important to choose the most effective treatment method and predict vital prognosis. The aim of this study was to investigate the effectiveness of immature granulocyte percentage (IG%) in grading AC severity.

methodsThis retrospective study was carried out on 528 patients hospitalized due to AC diagnosis. Demographic data, white blood cell (WBC) count, neutrophil lymphocyte ratio (NLR), IG%, C-reactive protein (CRP) levels, and imaging results of patients were recorded. Furthermore, patients' length of hospital stay was determined. Tokyo Guidelines were used to grade AC severity. According to this grading, patients were classified into three groups as grade 1 (mild), grade 2 (moderate), and grade 3 (severe) AC. Differences among groups were analyzed statistically.

resultsThere were 386 patients (73.1%) in the mild AC group, 102 patients (19.3%) in the moderate AC group, and 40 patients (7.6%) in the severe AC group. WBC, NLR, CRP and IG% were significant parameters in discriminating mild AC from moderate and severe AC. However, only IG% was a significant parameter in discriminating moderate AC from severe AC. Moreover, the power of IG% to discriminate between patients with mild and moderate AC and those with severe AC was dramatically higher than the other parameters.

conclusionIncreased IG% is seen as an effective and reliable predictor in the early determination of AC severity.

Indexed as

Cholecystitis, AcuteGranulocytesBiomarkersHumansNeutrophilsRetrospective StudiesBiomarkers

Identifiers

PMID36453788
PMCPMC10198320
OpenAlexW4310603751

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.