Evidence map›Paper›PMID 36453461›Full record

ArticleCell biology international2023

Low-dose dexamethasone promotes osteoblast viability by activating autophagy via the SGK1/FOXO3a signaling pathway.

Xiang-Hua Yu, Xiao-Ming Xu, Sheng-Xiang Zhang

Open access · hybridAbstract read
In one paragraph

Article in Cell biology international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Brain tumor research and treatment · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Xiang-Hua YuDental Disease Prevention and Control Institute of Minhang District, Shanghai, China.ORCID http://orcid.org/0000-0001-6340-3235
Xiao-Ming XuDental Disease Prevention and Control Institute of Minhang District, Shanghai, China.
Sheng-Xiang ZhangDepartment of Stomatology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Nanchang University · CN

Funding

Grants from the Minhang District Science and Technology Committee, Shanghai 2021MHZ045
6 · The paper itself

Abstract

Autophagy contributes to bone homeostasis and development under physiological conditions. Although previous studies have demonstrated the induction of the autophagy machinery by endogenous glucocorticoids (GCs), the precise mechanisms involved have not yet been clarified. The current study aimed to explore the effect of a low dose of GC (10

Indexed as

DexamethasoneGlucocorticoidsAnimalsApoptosisAutophagyBeclin-1Cell LineMiceOsteoblastsSignal TransductionBeclin-1DexamethasoneGlucocorticoidsautophagydexamethasoneFOXO3aosteoblastSGK1

Identifiers

PMID36453461
PMCPMC10108317
OpenAlexW4310569531

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.