ArticleG3 (Bethesda, Md.)2023
Genetics of tibia bone properties of crossbred commercial laying hens in different housing systems.
Article in G3 (Bethesda, Md.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Genetics of digital phenotypes of keel bone in layer chickens and correlations with keel bone fractures and deviations.Genetics, selection, evolution : GSE · 2025Article
- Leveraging genome-wide association analyses with chip and imputed data emerges potential pleiotropic region for four duck growth traits.Scientific reports · 2025Article
- The Gordon Memorial Lecture: genotype, phenotype, selection and more: improving the skeletal health of laying hens.British poultry science · 2025Article
- Article
- Genetic markers associated with bone composition in Rhode Island Red laying hens.Genetics, selection, evolution : GSE · 2023Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
Osteoporosis and bone fractures are a severe problem for the welfare of laying hens, with genetics and environment, such as housing system, each making substantial contributions to bone strength. In this work, we performed genetic analyses of bone strength, bone mineral density, and bone composition, as well as body weight, in 860 commercial crossbred laying hens from 2 different companies, kept in either furnished cages or floor pens. We compared bone traits between housing systems and crossbreds and performed a genome-wide association study of bone properties and body weight. As expected, the 2 housing systems produced a large difference in bone strength, with layers housed in floor pens having stronger bones. These differences were accompanied by differences in bone geometry, mineralization, and chemical composition. Genome scans either combining or independently analyzing the 2 housing systems revealed no genome-wide significant loci for bone breaking strength. We detected 3 loci for body weight that were shared between the housing systems on chromosomes 4, 6, and 27 (either genome-wide significant or suggestive) and these coincide with associations for bone length. In summary, we found substantial differences in bone strength, content, and composition between hens kept in floor pens and furnished cages that could be attributed to greater physical activity in pen housing. We found little evidence for large-effect loci for bone strength in commercial crossbred hens, consistent with a highly polygenic architecture for bone strength in the production environment. The lack of consistent genetic associations between housing systems in combination with the differences in bone phenotypes could be due to gene-by-environment interactions with housing system or a lack of power to detect shared associations for bone strength.
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