Evidence map›Paper›PMID 36453328›Full record

ArticleIndian journal of ophthalmology2022

Antibiotic susceptibility pattern of bacterial isolates from microbial keratitis in North and Central India: A multi centric study.

Ashi Khurana, Samrat Chatterjee, Arpan Gandhi, Prashant Borde, Sanjay Chanda, Sharad Nivrutti Gomase, Manvi Aggarwal, Gautam Singh Parmar, Atanu Majumdar, Priyanka Podder

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Indian journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Current status on antimicrobial resistance in keratitis.Indian journal of ophthalmology · 2026
    Article
  2. Antibiotic resistance mechanisms and global resistance patterns of Pseudomonas aeruginosa in microbial keratitis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  3. Article
  4. Article
  5. A comparison of antimicrobial regimen outcomes and antibiogram development in microbial keratitis: a prospective cohort study in Alexandria, Egypt.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ashi KhuranaDepartment of Cornea and Anterior Segment Services, CL Gupta Eye Institute, Moradabad, Uttar Pradesh; The Bodhya Eye Consortium: a. Dr Shroff's Charity Eye Hospital, New Delhi, India. b. Sadguru Netra Chikitsalaya, Jankikund, Chitrakoot, Madhya Pradesh, India. c. Regional Institute of Ophthalmology and Sitapur Eye Hospital, Sitapur, Uttar Pradesh, India. d. MGM Eye Institute, Raipur, Chhattisgarh, India. e. CL Gupta Eye Institute, Moradabad, Uttar Pradesh, India. f. LJ Eye Institute, Ambala City, Haryana, India.
Samrat ChatterjeeDepartment of Cornea and Anterior Segment Services, MGM Eye Institute, Raipur, Chhattisgarh; The Bodhya Eye Consortium: a. Dr Shroff's Charity Eye Hospital, New Delhi, India. b. Sadguru Netra Chikitsalaya, Jankikund, Chitrakoot, Madhya Pradesh, India. c. Regional Institute of Ophthalmology and Sitapur Eye Hospital, Sitapur, Uttar Pradesh, India. d. MGM Eye Institute, Raipur, Chhattisgarh, India. e. CL Gupta Eye Institute, Moradabad, Uttar Pradesh, India. f. LJ Eye Institute, Ambala City, Haryana, India.
Arpan GandhiDepartment of Laboratory Services, Dr Shroff's Charity Eye Hospital, New Delhi; The Bodhya Eye Consortium: a. Dr Shroff's Charity Eye Hospital, New Delhi, India. b. Sadguru Netra Chikitsalaya, Jankikund, Chitrakoot, Madhya Pradesh, India. c. Regional Institute of Ophthalmology and Sitapur Eye Hospital, Sitapur, Uttar Pradesh, India. d. MGM Eye Institute, Raipur, Chhattisgarh, India. e. CL Gupta Eye Institute, Moradabad, Uttar Pradesh, India. f. LJ Eye Institute, Ambala City, Haryana, India.
Prashant BordeDepartment of Cornea and Refractive Services, Sadguru Netra Chikitsalaya, Jankikund, Chitrakoot, Uttar Pradesh; The Bodhya Eye Consortium: a. Dr Shroff's Charity Eye Hospital, New Delhi, India. b. Sadguru Netra Chikitsalaya, Jankikund, Chitrakoot, Madhya Pradesh, India. c. Regional Institute of Ophthalmology and Sitapur Eye Hospital, Sitapur, Uttar Pradesh, India. d. MGM Eye Institute, Raipur, Chhattisgarh, India. e. CL Gupta Eye Institute, Moradabad, Uttar Pradesh, India. f. LJ Eye Institute, Ambala City, Haryana, India.
Sanjay ChandaDepartment of Cornea and Anterior Segment Services, CL Gupta Eye Institute, Moradabad, Uttar Pradesh; The Bodhya Eye Consortium: a. Dr Shroff's Charity Eye Hospital, New Delhi, India. b. Sadguru Netra Chikitsalaya, Jankikund, Chitrakoot, Madhya Pradesh, India. c. Regional Institute of Ophthalmology and Sitapur Eye Hospital, Sitapur, Uttar Pradesh, India. d. MGM Eye Institute, Raipur, Chhattisgarh, India. e. CL Gupta Eye Institute, Moradabad, Uttar Pradesh, India. f. LJ Eye Institute, Ambala City, Haryana, India.
Sharad Nivrutti GomaseDepartment of Cornea and Anterior Segment Services, MGM Eye Institute, Raipur, Chhattisgarh; The Bodhya Eye Consortium: a. Dr Shroff's Charity Eye Hospital, New Delhi, India. b. Sadguru Netra Chikitsalaya, Jankikund, Chitrakoot, Madhya Pradesh, India. c. Regional Institute of Ophthalmology and Sitapur Eye Hospital, Sitapur, Uttar Pradesh, India. d. MGM Eye Institute, Raipur, Chhattisgarh, India. e. CL Gupta Eye Institute, Moradabad, Uttar Pradesh, India. f. LJ Eye Institute, Ambala City, Haryana, India.
Manvi AggarwalDepartment of Cornea and Anterior Segment Services, Dr Shroff's Charity Eye Hospital, New Delhi; The Bodhya Eye Consortium: a. Dr Shroff's Charity Eye Hospital, New Delhi, India. b. Sadguru Netra Chikitsalaya, Jankikund, Chitrakoot, Madhya Pradesh, India. c. Regional Institute of Ophthalmology and Sitapur Eye Hospital, Sitapur, Uttar Pradesh, India. d. MGM Eye Institute, Raipur, Chhattisgarh, India. e. CL Gupta Eye Institute, Moradabad, Uttar Pradesh, India. f. LJ Eye Institute, Ambala City, Haryana, India.
Gautam Singh ParmarDepartment of Cornea and Refractive Services, Sadguru Netra Chikitsalaya, Jankikund, Chitrakoot, Uttar Pradesh; The Bodhya Eye Consortium: a. Dr Shroff's Charity Eye Hospital, New Delhi, India. b. Sadguru Netra Chikitsalaya, Jankikund, Chitrakoot, Madhya Pradesh, India. c. Regional Institute of Ophthalmology and Sitapur Eye Hospital, Sitapur, Uttar Pradesh, India. d. MGM Eye Institute, Raipur, Chhattisgarh, India. e. CL Gupta Eye Institute, Moradabad, Uttar Pradesh, India. f. LJ Eye Institute, Ambala City, Haryana, India.
Atanu MajumdarBiostatistician, Dr Shroff's Charity Eye Hospital/Sadguru Netra Chikitsalaya; The Bodhya Eye Consortium: a. Dr Shroff's Charity Eye Hospital, New Delhi, India. b. Sadguru Netra Chikitsalaya, Jankikund, Chitrakoot, Madhya Pradesh, India. c. Regional Institute of Ophthalmology and Sitapur Eye Hospital, Sitapur, Uttar Pradesh, India. d. MGM Eye Institute, Raipur, Chhattisgarh, India. e. CL Gupta Eye Institute, Moradabad, Uttar Pradesh, India. f. LJ Eye Institute, Ambala City, Haryana, India.
Priyanka PodderBiostatistician, Dr Shroff's Charity Eye Hospital/Sadguru Netra Chikitsalaya; The Bodhya Eye Consortium: a. Dr Shroff's Charity Eye Hospital, New Delhi, India. b. Sadguru Netra Chikitsalaya, Jankikund, Chitrakoot, Madhya Pradesh, India. c. Regional Institute of Ophthalmology and Sitapur Eye Hospital, Sitapur, Uttar Pradesh, India. d. MGM Eye Institute, Raipur, Chhattisgarh, India. e. CL Gupta Eye Institute, Moradabad, Uttar Pradesh, India. f. LJ Eye Institute, Ambala City, Haryana, India.
Dr. Shroff’s Charity Eye Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study was conducted to examine microbiological profile with their antibiotic sensitivity in cases of bacterial keratitis in north and central India to ensure appropriate use of antibiotics. Methods: The microbiology laboratory records of 228 patients with culture-proven bacterial keratitis from 1 Results: The prevalence of Staphylococcus aureus and Pseudomonas aeruginosa-induced keratitis was higher in northern India, whereas that by Streptococcus pneumoniae was more prevalent in central India. In central India, 100% of S. pneumoniae isolates were found to be sensitive to ceftriaxone compared to 79% in northern India (P = 0.017). In comparison to 67% of isolates from north India, 15% of S. aureus isolates from central India were found to be sensitive to ofloxacin (P = 0.009). Similarly, 23% of isolates from central India were found sensitive to amikacin compared to 65% of isolates from north India (P = 0.012). P. aeruginosa isolates from central India were found to be sensitive to ceftazidime in 63% of cases compared to 21% of isolates from north India (P = 0.034). Conclusion: Prevalence of bacteria and their susceptibility to antibiotics are not uniform across geography. Vancomycin remained the most effective drug in all gram-positive coccal infections. S. aureus susceptibility to amikacin was significantly greater in north India. P. aeruginosa showed less susceptibility as compared to previous reports.

Indexed as

Eye Infections, BacterialKeratitisAmikacinAnti-Bacterial AgentsHumansIndiaPseudomonas aeruginosaStaphylococcus aureusAmikacinAnti-Bacterial AgentsAntibiotic sensitivitybacterial keratitiscentral Indianorth India

Identifiers

PMID36453328
PMCPMC9940535
OpenAlexW4310595158

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.