Evidence map›Paper›PMID 36453291›Full record

ArticleThe Indian journal of medical research2022

Molecular characterization of BK virus detected in renal transplant patients in Sri Lanka: a preliminary study.

A K D Varuni Yashodha Ratnayake, Narmada Fernando, Thusitha Gajanayake, Shiroma Mangalika Handunnetti, S Chrishan Jude Jayamaha

Open access · diamondAbstract read
In one paragraph

Article in The Indian journal of medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

A K D Varuni Yashodha RatnayakeInstitute of Biochemistry, Molecular Biology & Biotechnology, University of Colombo, Colombo, Sri Lanka.
Narmada FernandoInstitute of Biochemistry, Molecular Biology & Biotechnology, University of Colombo, Colombo, Sri Lanka.
Thusitha GajanayakeFaculty of Science, Horizon Campus, Colombo, Sri Lanka.
Shiroma Mangalika HandunnettiInstitute of Biochemistry, Molecular Biology & Biotechnology, University of Colombo, Colombo, Sri Lanka.
S Chrishan Jude JayamahaDepartment of Virology, National Influenza Centre, Medical Research Institute, Colombo, Sri Lanka.
Medical Research Institute · LKUniversity of Colombo · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background & objectives: BK virus (BKV) is a polyomavirus and cause of a common infection after renal transplantation which could be preceded to BKV-associated nephropathy. It has four main subtypes (I-IV). BKV subtypes II and III are rare, whereas subtype I shows a ubiquitous distribution. The objective of the present study was to investigate the prevailing BKV subtypes and subgroups in renal transplant patients in Sri Lanka. Methods: The presence of BKV in urine was tested through virus load quantification by real-time PCR from 227 renal transplant patients who were suspected to have BKV infection. Of these patients only 41 were found to be BKV infected (>10 Results: Persistent BK viral loads varied from 1×10 Interpretation & conclusions: Findings from this preliminary study showed a high occurrence of subtype I, while the presence of subtype II, which is rare and less prevalent, was a novel finding for this Asian region. This emphasizes the need for further molecular and serological studies to determine the prevalence of different BKV subtypes in Sri Lanka.

Indexed as

BK VirusKidney TransplantationPolyomavirus InfectionsTumor Virus InfectionsDNA, ViralHumansPhylogenySri LankaViral LoadDNA, ViralBK virusrenal transplant patientsSri Lankasubtypes and subgroupsVP1 gene

Identifiers

PMID36453291
PMCPMC10101357
OpenAlexW4310566306

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.