Evidence map›Paper›PMID 36453025›Full record

ArticleDrug delivery2023

Ferric-loaded lipid nanoparticles inducing ferroptosis-like cell death for antibacterial wound healing.

Ying Zhou, Chong-Yang Cai, Cheng Wang, Guo-Ming Hu, Yu-Ting Li, Meng-Jiao Han, Shen Hu, Pu Cheng

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Ying ZhouDepartment of Gynecology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Chong-Yang CaiDepartment of Urology, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, China.
Cheng WangSchool of Pharmacy, Changzhou University, Changzhou, China.
Guo-Ming HuDepartment of General Surgery (Breast and Thyroid Surgery), Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Zhejiang, China.
Yu-Ting LiSchool of Pharmacy, Changzhou University, Changzhou, China.
Meng-Jiao HanDepartment of Nephrology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Shen HuDepartment of Obstetrics, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Pu ChengDepartment of Gynecology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Changzhou University · CNSecond Affiliated Hospital of Zhejiang University · CNImmune Regulation (United Kingdom) · GBSir Run Run Shaw Hospital · CNZhejiang Chinese Medical University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin infection is a major health issue that usually is caused by the continuous proliferation of bacteria in wounds. With the abuse of antibiotics worldwide, the battle against skin infection is becoming more and more difficult. Therefore, the development of new ways with different antibacterial mechanisms to current antibiotics is urgently needed. Inspired by the powerful inhibition of ferroptosis used in cancer therapy, here in our study, ferric-loaded lipid nanoparticles (Fe-LNPs) with unform size (∼130 nm) and surface charge (∼12 mV) were constructed and found to effectively inhibit the growth of both Gram positive (Staphylococcus aureus,

Indexed as

FerroptosisAnti-Bacterial AgentsCell DeathElectrolytesEscherichia coliLiposomesNanoparticlesStaphylococcus aureusWound HealingAnti-Bacterial AgentsElectrolytesLipid NanoparticlesLiposomesantibacterialferroptosislipid nanoparticlesSkin infectionwound healing

Identifiers

PMID36453025
PMCPMC9721425
OpenAlexW4310773490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.