Evidence map›Paper›PMID 36452897›Full record

ArticleFrontiers in medicine2022

Small airways dysfunction in patients with systemic sclerosis and interstitial lung disease.

Panagiotis K Panagopoulos, Andreas V Goules, Vasiliki E Georgakopoulou, Anastasios Kallianos, Eirini Chatzinikita, Vasileios C Pezoulas, Katerina Malagari, Dimitrios I Fotiadis, Panayiotis Vlachoyiannopoulos, Theodoros Vassilakopoulos and 1 more

Abstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Panagiotis K PanagopoulosDepartment of Pathophysiology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Andreas V GoulesDepartment of Pathophysiology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Vasiliki E GeorgakopoulouDepartment of Physiology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Anastasios KallianosDepartment of Physiology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Eirini ChatzinikitaDepartment of Physiology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Vasileios C PezoulasUnit of Medical Technology and Intelligent Information Systems, University of Ioannina, Ioannina, Greece.
Katerina Malagari2nd Department of Radiology, "Attikon" Hospital, University of Athens, Athens, Greece.
Dimitrios I FotiadisUnit of Medical Technology and Intelligent Information Systems, University of Ioannina, Ioannina, Greece.
Panayiotis VlachoyiannopoulosDepartment of Pathophysiology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Theodoros VassilakopoulosDepartment of Physiology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Athanasios G TzioufasDepartment of Pathophysiology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: A number of studies report small airways involvement in patients with systemic sclerosis (SSc). Furthermore, small airways dysfunction is increasingly recognized in patients with interstitial lung disease (ILD) of idiopathic or autoimmune etiology. The objectives of this study were to evaluate small airways function in SSc patients with ILD and explore the effect of treatment on small airways function by using conventional and contemporary pulmonary function tests (PFTs). Methods: This single-center, prospective, observational study included a total of 35 SSc patients, with and without ILD based on HRCT scan, evaluated by a special radiologist blindly. Clinical data were collected from all patients who were also assessed for HRCT findings of small airways disease. Small airways function was assessed by classic spirometry, measurement of diffusing capacity for carbon monoxide, body plethysmography, single breath nitrogen washout (N Results: Phase III slope Conclusion: Phase III slope

Indexed as

interstitial lung diseasephase III slopeN2SBWpulmonary function testsR5–R20small airways dysfunctionsystemic sclerosis

Identifiers

PMID36452897
PMCPMC9702077

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.