Evidence map›Paper›PMID 36452400›Full record

ArticleJournal of nutritional science2022

Dietary zinc restriction affects the expression of genes related to immunity and stress response in the small intestine of pigs.

Ramya Lekha Medida, Ashok Kumar Sharma, Yue Guo, Lee Johnston, Pedro E Urriola, Andres Gomez, Milena Saqui-Salces

Open access · goldAbstract read
In one paragraph

Article in Journal of nutritional science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ramya Lekha MedidaDepartment of Animal Science, University of Minnesota, 1988 Fitch Ave., 495K AS/VM, Saint Paul, MN 55108, USA.ORCID 0000-0002-1298-126X
Ashok Kumar SharmaDepartment of Animal Science, University of Minnesota, 1988 Fitch Ave., 495K AS/VM, Saint Paul, MN 55108, USA.ORCID 0000-0002-2264-7628
Yue GuoDepartment of Animal Science, University of Minnesota, 1988 Fitch Ave., 495K AS/VM, Saint Paul, MN 55108, USA.
Lee JohnstonWest Central Research and Outreach Center (WCROC), University of Minnesota, Morris, MN, USA.ORCID 0000-0003-4164-1835
Pedro E UrriolaDepartment of Animal Science, University of Minnesota, 1988 Fitch Ave., 495K AS/VM, Saint Paul, MN 55108, USA.
Andres GomezDepartment of Animal Science, University of Minnesota, 1988 Fitch Ave., 495K AS/VM, Saint Paul, MN 55108, USA.
Milena Saqui-SalcesDepartment of Animal Science, University of Minnesota, 1988 Fitch Ave., 495K AS/VM, Saint Paul, MN 55108, USA.ORCID 0000-0001-5848-0092
University of Minnesota · USUniversity of Minnesota Morris · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zinc (Zn) is an essential mineral and its deficiency manifests in non-specific clinical signs that require long time to develop. The response of swine intestine to Zn restriction was evaluated to identify early changes that can be indicative of Zn deficiency. Twenty-seven pigs (body weight = 77⋅5 ± 2⋅5 kg) were assigned to one of three diets: diet without added Zn (Zn-restricted diet, ZnR), and ZnR-supplemented with either 50 (Zn50) or 100 mg of Zn/kg of diet (Zn100) of Zn supplied by ZnCl

Indexed as

MalnutritionZincAnimalsBody WeightDietary SupplementsIntestine, SmallSwineZincGene expressionRNA-seqZinc deficiencyZinc transportersZIP4

Identifiers

PMID36452400
PMCPMC9705703
OpenAlexW4310597857

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.