Evidence map›Paper›PMID 36452178›Full record

ArticleJournal of oral microbiology2023

Identification of a growth factor required for culturing specific fastidious oral bacteria.

Pallavi Murugkar, Eric Dimise, Eric Stewart, Stéphane N Viala, Jon Clardy, Floyd E Dewhirst, Kim Lewis

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of oral microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Laser-assisted microbial culturomics.Nature communications · 2025
    Article
  2. Biofilm development ofMicrobiology spectrum · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Pallavi MurugkarAntimicrobial Discovery Center, Department of Biology, Northeastern University, 134 Mugar Hall, 360 Huntington Ave 02115, Boston, MA, USA.
Eric DimiseDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School 02115, Boston, MA, USA.
Eric StewartAntimicrobial Discovery Center, Department of Biology, Northeastern University, 134 Mugar Hall, 360 Huntington Ave 02115, Boston, MA, USA.
Stéphane N VialaDepartment of Microbiology, the Forsyth Institute, Cambridge, MA, USA.
Jon ClardyDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School 02115, Boston, MA, USA.
Floyd E DewhirstDepartment of Microbiology, the Forsyth Institute, Cambridge, MA, USA.
Kim LewisAntimicrobial Discovery Center, Department of Biology, Northeastern University, 134 Mugar Hall, 360 Huntington Ave 02115, Boston, MA, USA.
Harvard University · USNortheastern University · US

Funding

Cloud-Based Machine Learning and Biomarker Visual Analytics for Salivary ProteomicsR01DE016937 · NIDCR · ADA FORSYTH INSTITUTE, INC. · PI DEWHIRST, FLOYD E, MARK WELCH, JESSICA LEIGH · 2021 to 2025
$6.7M
NIDCR NIH HHS R01 DE016937
6 · The paper itself

Abstract

Aims: The aim of this research was to isolate oral bacteria that are dependent for growth on adjacent bacteria producing a required growth factor and to identify the chemical structure of the growth factor. Methods: Results: Analysis of the Conclusions: Addition of DHNA to culture media allows isolation of strains of several oral species that are not recovered using standard media.

Indexed as

1,4-dihydroxy-2-naphthoic acid (DHNA)bacterial cultivationgenomic analysisgrowth factorsmenaquinonePorphyromonas pasteri

Identifiers

PMID36452178
PMCPMC9704088
OpenAlexW4309938062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.