Evidence map›Paper›PMID 36452018›Full record

ArticleAsia Pacific allergy2022

Identification of fungi causing humidifier lung: 2 rare cases and a review of the literature.

Kai Ryu, Yuma Fukutomi, Kiyoshi Sekiya, Akemi Saito, Yuto Hamada, Kentaro Watai, Yosuke Kamide, Masami Taniguchi, Jun Araya, Kazuyoshi Kuwano and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Asia Pacific allergy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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  4. Asia Pacific allergy · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Kai RyuClinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital, Sagamihara, Japan.ORCID https://orcid.org/0000-0001-8765-6480
Yuma FukutomiClinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital, Sagamihara, Japan.ORCID https://orcid.org/0000-0001-9913-4524
Kiyoshi SekiyaClinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital, Sagamihara, Japan.
Akemi SaitoClinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital, Sagamihara, Japan.
Yuto HamadaClinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital, Sagamihara, Japan.ORCID https://orcid.org/0000-0002-3234-652X
Kentaro WataiClinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital, Sagamihara, Japan.ORCID https://orcid.org/0000-0001-9490-864X
Yosuke KamideClinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital, Sagamihara, Japan.ORCID https://orcid.org/0000-0002-7185-2273
Masami TaniguchiClinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital, Sagamihara, Japan.
Jun ArayaDivision of Respiratory Disease, Department of Internal Medicine, The Jikei University School of Medicine, Minato-ku, Japan.ORCID https://orcid.org/0000-0003-0491-6721
Kazuyoshi KuwanoDivision of Respiratory Disease, Department of Internal Medicine, The Jikei University School of Medicine, Minato-ku, Japan.ORCID https://orcid.org/0000-0003-0551-7386
Katsuhiko KameiDivision of Clinical Research, Medical Mycology Research Center, Chiba University, Chiba, Japan.ORCID https://orcid.org/0000-0002-6067-9049
National Sagamihara Hospital · JPChiba University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Humidifier lung (HL) is a hypersensitivity pneumonitis resulting from exposure to humidifiers, with fungi from the humidifier as one of the etiologic agents. However, identification of the fungal species responsible for each case can be challenging because of difficulties in culturing fungi, their accurate identification, and interpreting the results of specific serum IgG testing. Objective: To clarify the best way to determine the causative fungal species of each HL case. Methods: We report 2 cases with HL in which rare fungi were identified as causative agents. In addition, we searched MEDLINE for previous publications on HL caused by fungi and performed a literature review focusing on clinical testing for the determination of causal fungal species. Results: In our 2 cases, we identified Conclusion: We recommend performing culture of fungi from HW and specific serum IgG testing for the accurate determination of the causative fungal species in HL, and concordance between them serves as a rationale for the determination of causative fungal species.

Indexed as

Air conditionerFungiHumidifier lungHypersensitivity pneumonitisMycoses

Identifiers

PMID36452018
PMCPMC9669469
OpenAlexW4310599149

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.