Evidence map›Paper›PMID 36451860›Full record

ArticleTheranostics2022

Single-cell atlases link macrophages and CD8

Yuan Liang, Yezhen Tan, Bao Guan, Bin Guo, Mancheng Xia, Juan Li, Yue Shi, Zihui Yu, Qi Zhang, Di Liu and 7 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
13.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 57 citations in OpenAlex.

  1. Review
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  7. Medea: An omics AI agent for therapeutic discovery.bioRxiv : the preprint server for biology · 2026
    Article
  8. Article
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  11. Review
  12. Article
  13. IL-6Journal of translational medicine · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 3 countries.

Yuan LiangCAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China.
Yezhen TanCAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China.
Bao GuanDepartment of Urology, Peking University First Hospital, Beijing 100034, China.
Bin GuoCAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China.
Mancheng XiaDepartment of Urology, Peking University First Hospital, Beijing 100034, China.
Juan LiCAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China.
Yue ShiCAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China.
Zihui YuCAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China.
Qi ZhangCAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China.
Di LiuCore Facility for Protein Research, Institute of Biophysics, Chinese Academy of Science, Beijing 100101, China.
Xiaopeng YangCore Facility for Protein Research, Institute of Biophysics, Chinese Academy of Science, Beijing 100101, China.
Junfeng HaoCore Facility for Protein Research, Institute of Biophysics, Chinese Academy of Science, Beijing 100101, China.
Yanqing GongDepartment of Urology, Peking University First Hospital, Beijing 100034, China.
Muhammad ShakeelJamil-ur-Rahman Center for Genome Research, Dr. Panjwani Center for Molecular Medicine and Drug Research, ICCBS, University of Karachi, Karachi, Pakistan.
Liqun ZhouDepartment of Urology, Peking University First Hospital, Beijing 100034, China.
Weimin CiCAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing 100101, China.
Xuesong LiDepartment of Urology, Peking University First Hospital, Beijing 100034, China.
Beijing Institute of Genomics · CNChinese Academy of Sciences · CNPeking University · CNPeking University First Hospital · CNUniversity of Chinese Academy of Sciences · CNUniversity of Karachi · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Carcinoma, Transitional CellUrinary Bladder NeoplasmsCD8-Positive T-LymphocytesDisease ProgressionHumansImmune Checkpoint InhibitorsImmunologic FactorsImmunosuppressive AgentsImmunotherapyMacrophagesTumor MicroenvironmentImmune Checkpoint InhibitorsImmunologic FactorsImmunosuppressive AgentsImmunosuppressionImmunotherapySingle-cell RNA sequencingTumor microenvironmentUrothelial carcinoma

Identifiers

PMID36451860
PMCPMC9706581
OpenAlexW4310602683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.