Evidence map›Paper›PMID 36451660›Full record

ReviewF1000Research2022

Role of RAS signaling in ovarian cancer.

Lubna Therachiyil, Anjana Anand, Abdullah Azmi, Ajaz Bhat, Hesham M Korashy, Shahab Uddin

Open access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Ovarian Cancer Susceptibility and Chemosensitivity to KRAS Modulation.International journal of molecular sciences · 2026
    Article
  6. Article
  7. Review
  8. Review
  9. Functional validation of somatic variability inCancer biology & therapy · 2025
    Article
  10. Review
  11. Ovarian Cancer: Multi-Omics Data Integration.International journal of molecular sciences · 2025
    Review
  12. Article
  13. Review
  14. Review
  15. Frontiers in oncology · 2025
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lubna TherachiyilHamad Medical Corporation, Doha, Qatar, 3050, Qatar.
Anjana AnandHamad Medical Corporation, Doha, Qatar, 3050, Qatar.
Abdullah AzmiHamad Medical Corporation, Doha, Qatar, 3050, Qatar.
Ajaz BhatSidra Medicine, Doha, 26999, Qatar.
Hesham M KorashyDepartment of Pharmaceutical Sciences, College of Pharmacy, QU Health, Qatar University, Doha, 2713, Qatar.
Shahab UddinHamad Medical Corporation, Doha, Qatar, 3050, Qatar.ORCID 0000-0003-1886-6710
Hamad Medical Corporation · QAQatar University · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The RAS family of proteins is among the most frequently mutated genes in human malignancies. In ovarian cancer (OC), the most lethal gynecological malignancy,

Indexed as

Ovarian NeoplasmsProto-Oncogene Proteins p21(ras)AnimalsCarcinogenesisFemaleHumansMicePhosphatidylinositol 3-KinasesSignal TransductionPhosphatidylinositol 3-KinasesProto-Oncogene Proteins p21(ras)cell signalingmutationOncogeneOvarian cancersRAS

Identifiers

PMID36451660
PMCPMC9669513
OpenAlexW4308354281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.