Evidence map›Paper›PMID 36451406›Full record

ArticleMedicine2022

Opioids for treating refractory dyspnea in patients with heart failure: A protocol for systematic review and meta-analysis.

Jianguo Lyu, Xianghong Sun, Mingming Chen, Sijia Li

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Jianguo LyuIntensive Care Unit, Shengjing Hospital of China Medical University, Liaoning, China.
Xianghong SunIntensive Care Unit, Shengjing Hospital of China Medical University, Liaoning, China.
Mingming ChenInterventional Ward, Shengjing Hospital of China Medical University, Liaoning, China.
Sijia LiInterventional Ward, Shengjing Hospital of China Medical University, Liaoning, China.ORCID 0000-0001-8001-5971
S.P.E.C.I.E.S. · USChina Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDyspnea is a hallmark symptom of heart failure. The existing clinical studies have indicated that opioid can effectively improve the clinical symptoms of heart failure patients with dyspnea. However, there has not been any relevant systematic review and meta-analysis. We performed a protocol for systematic review and meta-analysis to evaluate the safety and efficacy of opioid therapy for heart failure patients with refractory dyspnea.

methodsWe searched 3 foreign electronic databases (Cochrane Library, Embase, Pubmed) and 4 Chinese electronic databases (China National Knowledge Infrastructure, Wang Fang Database, Chinese Biomedical Literature Database and Chinese Scientific Journal Database) to collect potential studies from their inceptions to October 2022. The risk of bias in the included articles was assessed according to the Risk of Bias Assessment Tool in Cochrane Handbook of Systematic Reviews (5th edition). The quality of evidence was assessed by the Grading of Recommendations Assessment, Development and Evaluation approach. Data were analyzed using the RevMan Version 5.4.1.

resultsThis study will evaluate whether opioid is effective and safe for treating refractory dyspnea in patients with heart failure.

conclusionThis meta-analysis will provide comprehensive evidence of opioid therapy for heart failure patients with dyspnea.

Indexed as

Analgesics, OpioidHeart FailureDyspneaHumansMeta-Analysis as TopicSystematic Reviews as TopicAnalgesics, Opioid

Identifiers

PMID36451406
PMCPMC9704871
OpenAlexW4310468027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.