ArticleNature2023
Social trauma engages lateral septum circuitry to occlude social reward.
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Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.
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79citing papers in PubMed
28.1field-weighted citation impact, top 1% of its field
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Who cites it
79 citing papers in PubMed, 137 citations in OpenAlex.
- Multi-omics characterization of chronic social defeat stress recall-activated nuclei in Arc-GFP mice.Molecular psychiatry · 2026Article
- ATP release from the amygdala-prefrontal pathway regulates vulnerability to social stress in male mice.Molecular psychiatry · 2026Article
- Article
- Lateral septum GABAergic neurons mediate the effects of dexmedetomidine on allodynia and sleep in a male mouse model of neuropathic pain.Nature communications · 2026Article
- Article
- Tetrodotoxin-resistant NaMolecular psychiatry · 2026Article
- Sexual Dimorphism in c-Fos Networks Governing Aggression.bioRxiv : the preprint server for biology · 2026Article
- Major depressive disorder shares systemic immune signatures and potential therapeutic targets with inflammatory skin diseases.Molecular psychiatry · 2026Article
- Cell Type-Specific Downregulation of Dnmt3a in Nucleus Accumbens Oligodendrocytes Prevents Myelin Damage and Reduces Susceptibility to Social Stress in Male Mice.Biomolecules · 2026Article
- Review
- Bidirectional regulation of social memory by two distinct types of GABAergic neurons in the lateral septum.Nature communications · 2026Article
- Social hierarchy and resilience affect stress-induced PTSD via Uba7 gene expression and subsequent inflammation in microglia of the mPFC.Molecular psychiatry · 2026Article
- The lateral septum orchestrates state-dependent modulation of associative threat memory dynamics across the ovarian hormone cycle.bioRxiv : the preprint server for biology · 2026Article
- ATP Release Deficiency through Astrocytic Connexin 43 in the Dorsal Hippocampus Promotes Depressive- and Anxiety-Like Behaviors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Distinct and Shared Brain-Wide Activation Patterns in Mouse Models of Inflammatory and Neuropathic Pain.Journal of pain research · 2026Article
- Neurobiology of resilience to early life stress.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Role of molecularly defined lateral septum cell types and circuits in social behaviors.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Advancing scientific understanding of the drive to socially engage: from broad constructs to transdiagnostic 'building blocks'.Molecular psychiatry · 2026Review
- Alcohol Facilitates Social Dominance Via Activating Dopamine 1 Receptor-expressing Neurons in the Lateral Septum of Male Mice.Molecular neurobiology · 2025Article
- Deficiency of Shank3 in the nucleus accumbens reveals a loss of social-specific motivation.Communications biology · 2025Article
19 more citing papers are in PubMed but not listed here.
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Authors and funding
13 authors at 1 institution in 1 country.
Long LiNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-1354-8468
Romain Durand-de CuttoliNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0003-0240-7608
Antonio V AubryNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
C Joseph BurnettNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Flurin CathomasNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Lyonna F PariseNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-7527-8977
Kenny L ChanNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Carole MorelFriedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-5076-1938
Chongzhen YuanFriedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Yusuke ShimoNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Hsiao-Yun LinFriedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jun WangFriedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Scott J RussoNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA. scott.russo@mssm.edu.ORCID http://orcid.org/0000-0002-6470-1805
Allen Institute for Brain Science · US
Funding
ResourceP40OD010996 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STRICK, PETER · 2012 to 2024
$11.0MROLE OF PERIPHERAL IMMUNE-DERIVED MMP8 IN STRESS SUSCEPTIBILITYR01MH104559 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SCOTT JAMES RUSSO · 2014 to 2026
$9.2MNeural Circuit Mechanisms of Stress-Impaired Social RewardR01MH127820 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI RUSSO, SCOTT JAMES · 2021 to 2025
$3.5MRole of lateral habenula orexin receptor signaling in aggressive social behaviorR01MH114882 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI RUSSO, SCOTT JAMES · 2017 to 2021
$2.7MSex Differences in Neural Circuit Mechanisms of AggressionR01MH133299 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SCOTT JAMES RUSSO · 2023 to 2026
$2.6MRapid and Long-Lasting Antidepressant Action by Targeting Midbrain HCN ChannelsR01MH120637 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI RUSSO, SCOTT JAMES · 2019 to 2022
$1.8MRole of VTA-Amygdala Neural Circuit in Mediating Anxiety-Related BehaviorsR01MH120514 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MOREL, CAROLE S, RUSSO, SCOTT JAMES · 2021 to 2022
$847kNIH HHS P40 OD010996NIMH NIH HHS R01 MH104559NIMH NIH HHS R01 MH114882NIMH NIH HHS R01 MH120514NIMH NIH HHS R01 MH120637NIMH NIH HHS R01 MH127820NIMH NIH HHS R01 MH133299
Abstract
In humans, traumatic social experiences can contribute to psychiatric disorders
Indexed as
Neural PathwaysPsychological TraumaRewardSeptal NucleiSocial BehaviorStress, PsychologicalAnimalsBrainCalciumFemaleMaleMiceMice, Inbred C57BLNeuronsNeurotensinOptogeneticsCalciumFos protein, mouseNeurotensinProto-Oncogene Proteins c-fos
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.