Evidence map›Paper›PMID 36450980›Full record

ArticleNature2022

Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis.

Zaili Luo, Mingyang Xia, Wei Shi, Chuntao Zhao, Jiajia Wang, Dazhuan Xin, Xinran Dong, Yu Xiong, Feng Zhang, Kalen Berry and 26 more

RetractedAbstract readRetracted Publication
PubMed Publisher
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 57 citations in OpenAlex.

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  13. Opposite patterns of association of TWIST1 expression with patient survival in SHH and Group 4 medulloblastoma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
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  16. Review
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  19. Review
  20. High Expression of GABABrain sciences · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

36 authors at 8 institutions in 4 countries.

Zaili Luo *Brain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0002-8773-604X
Mingyang Xia *Key Laboratory of Birth Defects, Children's Hospital of Fudan University, Fudan University, Shanghai, China.
Wei Shi *Department of Neurosurgery, Children's Hospital of Fudan University, Shanghai, China.
Chuntao Zhao *Brain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Jiajia Wang *Department of Pediatric Neurosurgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Dazhuan XinBrain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Xinran DongKey Laboratory of Birth Defects, Children's Hospital of Fudan University, Fudan University, Shanghai, China.
Yu XiongObstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Feng ZhangBrain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Kalen BerryBrain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Sean OgurekBrain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Xuezhao LiuBrain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Rohit RaoBrain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Rui XingBrain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Lai Man Natalie WuBrain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Siying CuiKey Laboratory of Birth Defects, Children's Hospital of Fudan University, Fudan University, Shanghai, China.
Lingli XuKey Laboratory of Birth Defects, Children's Hospital of Fudan University, Fudan University, Shanghai, China.
Yifeng LinKey Laboratory of Birth Defects, Children's Hospital of Fudan University, Fudan University, Shanghai, China.
Wenkun MaDepartment of Pediatric Neurosurgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shuaiwei TianDepartment of Pediatric Neurosurgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Qi XieSchool of Life Sciences, Westlake University, Hangzhou, China.
Li ZhangBrain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Mei XinBrain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0002-5732-7501
Xiaotao WangDepartment of Biochemistry and Molecular Genetics, Feinberg School of Medicine Northwestern University, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-3531-2157
Feng YueDepartment of Biochemistry and Molecular Genetics, Feinberg School of Medicine Northwestern University, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-7954-5462
Haizi ZhengBrain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Yaping LiuBrain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Charles B StevensonBrain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Peter de BlankBrain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0001-6623-3040
John P PerentesisBrain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Richard J GilbertsonCancer Research UK Cambridge Centre, CRUK Cambridge Institute, Li Ka Shing Centre, Cambridge, UK.ORCID http://orcid.org/0000-0001-7539-9472
Hao LiDepartment of Neurosurgery, Children's Hospital of Fudan University, Shanghai, China. lihao7272@163.com.ORCID http://orcid.org/0000-0001-7755-1749
Jie MaDepartment of Pediatric Neurosurgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. majie@xinhuamed.com.cn.ORCID http://orcid.org/0000-0003-3776-4429
Wenhao ZhouKey Laboratory of Birth Defects, Children's Hospital of Fudan University, Fudan University, Shanghai, China. zhouwenhao@fudan.edu.cn.ORCID http://orcid.org/0000-0001-8956-7238
Michael D TaylorDevelopmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0001-7009-3466
Q Richard LuBrain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Richard.Lu@cchmc.org.ORCID http://orcid.org/0000-0001-6846-9014
Cincinnati Children's Hospital Medical Center · USChildren's Hospital of Fudan University · CNShanghai Jiao Tong University · CNNorthwestern University · USCancer Research UK Cambridge Center · GBHospital for Sick Children · CAState Key Laboratory of Oncogene and Related Genes · CNWestlake University · CN

Funding

The DNA Damage Response and Tumorigenesis in the BrainP01CA096832 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI BAKER, SUZANNE J. · 2003 to 2025
$38.0M
Cancer Research UK 22492Cancer Research UK 26398Cancer Research UK 28598NCI NIH HHS P01 CA096832
6 · The paper itself

Abstract

Medulloblastoma (MB) is the most common malignant childhood brain tumour

Indexed as

Brain NeoplasmsCell Transformation, NeoplasticFetusMedulloblastomaCerebellar NeoplasmsCerebellumHeterogeneous-Nuclear RibonucleoproteinsHumansNeural Stem CellsPrognosisSOXC Transcription FactorsHeterogeneous-Nuclear RibonucleoproteinsHNRNPH1 protein, humanSOX11 protein, humanSOXC Transcription Factors

Identifiers

PMID36450980
OpenAlexW4310438905

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.