Evidence map›Paper›PMID 36450464›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Resolution of Laryngeal Ulceration with Prednisolone Therapy in a Patient with Crohn's Disease.

Yi-Ling Ko, Hiroki Matsuoka, Ryohei Nomaru, So Imakiire, Hideto Sakisaka, Satoshi Matsuoka, Nobuaki Kuno, Koichi Abe, Sadahiro Funakoshi, Yusuke Ishida and 4 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Epiglottic Ulceration as an Initial Manifestation of Crohn's Disease.Journal of general and family medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Yi-Ling KoDepartment of Gastroenterology and Medicine, Fukuoka University Hospital, Japan.
Hiroki MatsuokaDepartment of Gastroenterology and Medicine, Fukuoka University Hospital, Japan.
Ryohei NomaruDepartment of Gastroenterology and Medicine, Fukuoka University Hospital, Japan.
So ImakiireDepartment of Gastroenterology and Medicine, Fukuoka University Hospital, Japan.
Hideto SakisakaDepartment of Gastroenterology and Medicine, Fukuoka University Hospital, Japan.
Satoshi MatsuokaDepartment of Gastroenterology and Medicine, Fukuoka University Hospital, Japan.
Nobuaki KunoDepartment of Gastroenterology and Medicine, Fukuoka University Hospital, Japan.
Koichi AbeDepartment of Gastroenterology and Medicine, Fukuoka University Hospital, Japan.
Sadahiro FunakoshiDepartment of Gastroenterology and Medicine, Fukuoka University Hospital, Japan.
Yusuke IshidaDepartment of Gastroenterology and Medicine, Fukuoka University Hospital, Japan.
Hideki IshibashiDepartment of Gastroenterology and Medicine, Fukuoka University Hospital, Japan.
Shinpei MiyagiDepartment of Otorhinolaryngology, Head and Neck Surgery, Fukuoka University Hospital, Japan.
Toshifumi SakataDepartment of Otorhinolaryngology, Head and Neck Surgery, Fukuoka University Hospital, Japan.
Fumihito HiraiDepartment of Gastroenterology and Medicine, Fukuoka University Hospital, Japan.
Fukuoka University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 23-year-old man diagnosed with Crohn's disease (CD) was treated with infliximab. He developed new-onset sore throat and dysphagia during admission, and nasopharyngoscopy revealed epiglottic ulceration. Laryngeal ulceration was considered as an extraintestinal manifestation of CD owing to treatment failure with antibiotics and hydrocortisone. This strongly suggested that laryngeal ulceration was a complication of CD because of the rapid improvement in the symptoms and lesions after prednisolone administration. Furthermore, this treatment process demonstrated the superior anti-inflammatory effect of prednisolone over that of hydrocortisone and supported the assumption of inflammation related to CD.

Indexed as

Crohn DiseaseAdultHumansHydrocortisoneInfliximabMalePrednisoloneTreatment FailureYoung AdultHydrocortisoneInfliximabPrednisoloneCrohn's diseaseextraintestinal manifestationlaryngeal ulcerationprednisolone

Identifiers

PMID36450464
PMCPMC10400401
OpenAlexW4310570046

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.