Evidence map›Paper›PMID 36450369›Full record

SynthesisEuropean respiratory review : an official journal of the European Respiratory Society2022

Respiratory muscle training in neuromuscular disease: a systematic review and meta-analysis.

Kathryn Watson, Thorlene Egerton, Nicole Sheers, Sarah Retica, Rebekah McGaw, Talia Clohessy, Penny Webster, David J Berlowitz

Open access · diamondAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in European respiratory review : an official journal of the European Respiratory Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 7 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 7 syntheses or guidelines pooled it, 42 citations in OpenAlex.

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  7. Effect of respiratory training on swallowing function in swallowing disorders: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Kathryn WatsonDepartment of Physiotherapy, Fiona Stanley Hospital, Perth, Australia.
Thorlene EgertonDepartment of Physiotherapy, The University of Melbourne, Melbourne, Australia.
Nicole SheersDepartment of Respiratory and Sleep Medicine, Austin Hospital, Heidelberg, Australia.ORCID https://orcid.org/0000-0003-1847-4266
Sarah ReticaDepartment of Physiotherapy, Austin Hospital, Heidelberg, Australia.
Rebekah McGawDepartment of Physiotherapy, Austin Hospital, Heidelberg, Australia.
Talia ClohessyDepartment of Physiotherapy, Austin Hospital, Heidelberg, Australia.
Penny WebsterHunter New England Local Health District, Newcastle, Australia.ORCID https://orcid.org/0000-0002-5834-4047
David J BerlowitzDepartment of Physiotherapy, The University of Melbourne, Melbourne, Australia david.berlowitz@austin.org.au.ORCID https://orcid.org/0000-0003-2543-8722
Austin Hospital · AUThe University of Melbourne · AUFiona Stanley Hospital · AUHunter New England Local Health District · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeuromuscular disease causes a progressive decline in ventilatory function which respiratory muscle training may address. Previous systematic reviews have focussed on single diseases, whereas this study systematically reviewed the collective evidence for respiratory muscle training in children and adults with any neuromuscular disease.

methodsSeven databases were searched for randomised controlled trials. Three reviewers independently reviewed eligibility, extracted characteristics, results, determined risk of bias and combined results using narrative synthesis and meta-analysis.

results37 studies (40 publications from 1986-2021, n=951 participants) were included. Respiratory muscle training improved forced vital capacity (standardised mean difference (SMD) 0.40 (95% confidence interval 0.12-0.69)), maximal inspiratory (SMD 0.53 (0.21-0.85)) and maximal expiratory pressure (SMD 0.70 (0.35-1.04)) compared to control (usual care, sham or alternative treatment). No impact on cough, dyspnoea, voice, physical capacity or quality of life was detected. There was high degree of variability between studies. DISCUSSION: Study heterogeneity (children and adults, different diseases, interventions, dosage and comparators) suggests that the results should be interpreted with caution. Including all neuromuscular diseases increased the evidence pool and tested the intervention overall.

conclusionsRespiratory muscle training improves lung volumes and respiratory muscle strength in neuromuscular disease, but confidence is tempered by limitations in the underlying research.

Indexed as

Neuromuscular DiseasesQuality of LifeAdultBreathing ExercisesChildCoughHumansRespiratory Muscles

Identifiers

PMID36450369
PMCPMC9724913
OpenAlexW4310372182

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.