Evidence map›Paper›PMID 36450137›Full record

ArticleBlood2023

Somatic TP53 mutations are preleukemic events in acute lymphoblastic leukemia.

Guranda Chitadze, Anna Stengel, Cathrin John-Klaua, Julien Bruckmüller, Heiko Trautmann, Michaela Kotrova, Franziska Darzentas, Miriam Kelm, Karol Pal, Nikos Darzentas and 12 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. EJHaem · 2024
    Article
  4. Article
  5. Article
  6. Genetically Distinct Acute Megakaryoblastic Leukemia following Low Hypodiploid B-Lymphoblastic Leukemia linked byPediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 5 institutions in 2 countries.

Guranda ChitadzeMedical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.ORCID 0000-0001-9609-4643
Anna StengelMunich Leukemia Laboratory, Munich, Germany.
Cathrin John-KlauaMedical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.
Julien BruckmüllerMedical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.ORCID 0000-0002-3900-9833
Heiko TrautmannMedical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.
Michaela KotrovaMedical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.
Franziska DarzentasMedical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.
Miriam KelmMedical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.
Karol PalMedical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.ORCID 0000-0002-7726-4691
Nikos DarzentasMedical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.
Lorenz BastianMedical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.
Britta KehdenMedical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.
Wiebke WesselsMedical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.
Aeint-Steffen StröhMedical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.
Hans-Heinrich ObergInstitute of Immunology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.
Philipp M AltrockDepartment of Evolutionary Theory, Max Planck Institute for Evolutionary Biology, Ploen, Germany.
Constance BaerMunich Leukemia Laboratory, Munich, Germany.
Manja MeggendorferMunich Leukemia Laboratory, Munich, Germany.
Nicola GökbugetDepartment of Medicine II, Goethe University Hospital, Frankfurt, Germany.
Claudia D BaldusMedical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.
Claudia HaferlachMunich Leukemia Laboratory, Munich, Germany.
Monika BrüggemannMedical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.ORCID 0000-0001-5514-5010
Christian-Albrechts-Universität zu Kiel · DEMunich Leukemia Laboratory (Germany) · DECentral European Institute of Technology · CZGoethe University Frankfurt · DEMax Planck Institute for Evolutionary Biology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Precursor Cell Lymphoblastic Leukemia-LymphomaHumansMutationTumor Suppressor Protein p53TP53 protein, humanTumor Suppressor Protein p53

Identifiers

PMID36450137
PMCPMC10651768
OpenAlexW4310443772

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.