ArticleThe Plant cell2023
Different combinations of laccase paralogs nonredundantly control the amount and composition of lignin in specific cell types and cell wall layers in Arabidopsis.
Article in The Plant cell, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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32 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Integrated QTL Mapping, Meta-Analysis, and RNA-Sequencing Reveal Candidate Genes for Maize Deep-Sowing Tolerance.International journal of molecular sciences · 2023Pooled it
- Positional grammar of transcription factor binding partitions developmental and stress-response regulation in plants.Nature communications · 2026Article
- Histone demethylase CsJMJ12 enhances resistance of Navel orange to Penicillium digitatum via H3K27me3 demethylation.Journal of advanced research · 2026Article
- Flavescence dorée phytoplasma infection represses the transcription of the lignin pathway inFrontiers in plant science · 2026Article
- Trehalose-mediated reshaping of the rhizosphere microbiome drives tea root rot progression.Frontiers in microbiology · 2026Article
- Storage domains of coniferin in cell wall forming tracheid cells in Pinus thunbergii stems evaluated by cryo microscopic chemical analyses.Scientific reports · 2025Article
- A needle in the haystack: Single-cell omics of the distinct xylem differentiation programs in gymnosperms and angiosperms.The Plant cell · 2025Article
- Physiological roles of lignins - tuning cell wall hygroscopy and biomechanics.The New phytologist · 2025Review
- Identification of post-transcriptional regulation reveals complexity in peanut pod development by Direct RNA.aBIOTECH · 2025Article
- A Cotton Laccase Confers Disease Resistance Against Verticillium dahliae by Promoting Cell Wall Lignification.Molecular plant pathology · 2025Article
- Modulation of morphogenesis and metabolism by plant cell biomechanics: from model plants to traditional herbs.Horticulture research · 2025Article
- Forage biomass and nutrient quality in brown midrib (BMR) compared to conventionalJournal of advanced veterinary and animal research · 2025Article
- Transcriptome study on the effect of leaf-fruit ratio on molecular regulation mechanism of Camellia oleifera.BMC plant biology · 2025Article
- Advanced imaging-enabled understanding of cell wall remodeling mechanisms mediating plant drought stress tolerance.Frontiers in plant science · 2025Review
- Genome-wide identification, classification, and expression profiling of LAC gene family in sesame.BMC plant biology · 2024Article
- CsLAC4, regulated by CsmiR397a, confers drought tolerance to the tea plant by enhancing lignin biosynthesis.Stress biology · 2024Article
- Unveiling Key Genes and Unique Transcription Factors Involved in Secondary Cell Wall Formation inInternational journal of molecular sciences · 2024Article
- Extracellular vesicles of Norway spruce contain precursors and enzymes for lignin formation and salicylic acid.Plant physiology · 2024Article
- Article
- The Characterization of a Novel PrMADS11 Transcription Factor fromInternational journal of molecular sciences · 2024Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vascular plants reinforce the cell walls of the different xylem cell types with lignin phenolic polymers. Distinct lignin chemistries differ between each cell wall layer and each cell type to support their specific functions. Yet the mechanisms controlling the tight spatial localization of specific lignin chemistries remain unclear. Current hypotheses focus on control by monomer biosynthesis and/or export, while cell wall polymerization is viewed as random and nonlimiting. Here, we show that combinations of multiple individual laccases (LACs) are nonredundantly and specifically required to set the lignin chemistry in different cell types and their distinct cell wall layers. We dissected the roles of Arabidopsis thaliana LAC4, 5, 10, 12, and 17 by generating quadruple and quintuple loss-of-function mutants. Loss of these LACs in different combinations led to specific changes in lignin chemistry affecting both residue ring structures and/or aliphatic tails in specific cell types and cell wall layers. Moreover, we showed that LAC-mediated lignification has distinct functions in specific cell types, waterproofing fibers, and strengthening vessels. Altogether, we propose that the spatial control of lignin chemistry depends on different combinations of LACs with nonredundant activities immobilized in specific cell types and cell wall layers.
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