Evidence map›Paper›PMID 36449518›Full record

ArticlePloS one2022

Ultrasound classification of non-mass breast lesions following BI-RADS presents high positive predictive value.

Mingnan Lin, Size Wu

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  4. Review
  5. Review
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  8. Article
  9. Approach to Nonmass Lesions on Breast Ultrasound.The Indian journal of radiology & imaging · 2024
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mingnan LinDepartment of Ultrasound, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, People's Republic of China.
Size WuDepartment of Ultrasound, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, People's Republic of China.ORCID 0000-0002-1086-764X
Hainan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the positive predictive value of ultrasound classification of non-mass breast lesions (NMLs) following breast imaging reporting and data system (BI-RADS), and enhance understanding of NMLs. MATERIALS AND

methodsFifty-nine women with 59 ultrasound-detected breast NMLs were finally enrolled. The ultrasound (US) features of breast NMLs were analyzed; the incidence of malignant NMLs was calculated; the malignancy risk stratification of US for breast NMLs was established using BI-RADS.

resultsThe incidence of malignant NMLs was 4.59% of all breast carcinoma. Non-ductal hypoechoic area, microcalcifications and posterior shadowing are the main US features of malignant NMLs, and there were significant differences between malignant and benign NMLs for microcalcifications and posterior shadowing. Taking BI-RADS 4B as a cutoff value, the sensitivity, specificity, area under the receiver operating characteristic curve (AUC), positive and negative predictive values, and odds ratio of the BI-RADS category were 82.98%,41.67%,0.62,84.78%,38.46% and 3.48, respectively.

conclusionsStratifying the malignancy risk of breast NMLs using the BI-RADS the sensitivity and positive and predictive value are promising, but the likelihood of malignancy of malignant NMLs is underestimated, and that of benign NMLs is overestimated. The solution may be that to separate NMLs from breast masses and use different malignancy risk stratification protocols.

Indexed as

CalcinosisLymphoma, FollicularBreastFemaleHumansPredictive Value of TestsUltrasonographyUltrasonography, Mammary

Identifiers

PMID36449518
PMCPMC9710769
OpenAlexW4310434804

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.